Prospective study of PAPNET: review of 25 656 Pap smears negative on manual screening and rapid rescreening

被引：10

作者：

Halford, JA ^{[1
]}

Wright, RG ^{[1
]}

Ditchmen, EJ ^{[1
]}

机构：

[1] Queensland Med Lab, Dept Anat Pathol, Cytol Sect, Brisbane, Qld 4101, Australia

来源：

CYTOPATHOLOGY | 1999年 / 10卷 / 05期

关键词：

PAPNET; rapid rescreening; false-negative smears; random rescreening;

D O I：

10.1046/j.1365-2303.1999.00186.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In this prospective study, 27014 Pap smears were selected for PAPNET review on the request of the referring practitioner or patient. Smears that were negative on routine manual screening were submitted for rapid rescreening. Smears considered normal after these two manual screens (n = 25656) were reviewed using the PAPNET testing system. Routine manual screening identified 1340 (4.96%) of the smears as abnormal, and a further 18 (0.07%) abnormalities were detected by rapid rescreening. PAPNET review identified an additional 102 (0.4%) abnormal smears, including 10 histologically confirmed high grade lesions. The use of PAPNET testing following routine manual screening and rapid rescreening in tandem, enables cytologists to detect additional diagnostically significant abnormalities and reduce the rate of false-negative smears.

引用

页码：317 / 323

页数：7

共 16 条

[1] RAPID CERVICAL CYTOLOGY SCREENING [J].

BAKER, A ;

MELCHER, DH .

CYTOPATHOLOGY, 1991, 2 (06) :299-301

[2] NEURAL-NETWORK PROCESSING CAN PROVIDE MEANS TO CATCH ERRORS THAT SLIP THROUGH HUMAN SCREENING OF PAP SMEARS [J].

BOON, ME ;

KOK, LP .

DIAGNOSTIC CYTOPATHOLOGY, 1993, 9 (04) :411-416

[3]

*COMM DEP HLTH FAM, 1996, PERF STAND AUSTR LAB

[4] ATYPICAL SQUAMOUS CELLS OF UNDETERMINED SIGNIFICANCE - INTERLABORATORY COMPARISON AND QUALITY ASSURANCE MONITORS [J].

DAVEY, DD ;

NARYSHKIN, S ;

NIELSEN, ML ;

KLINE, TS .

DIAGNOSTIC CYTOPATHOLOGY, 1994, 11 (04) :390-396

[5] Evaluation of the PAPNET system in a general pathology service [J].

Farnsworth, A ;

Chambers, FM ;

Goldschmidt, CS .

MEDICAL JOURNAL OF AUSTRALIA, 1996, 165 (08) :429-431

[6] Rapid screening of cervical smears as a method of internal quality control - For how long should we rescreen? [J].

Farrell, DJ ;

Bilkhu, S ;

Gibson, LM ;

Cummings, L ;

Wadehra, V .

ACTA CYTOLOGICA, 1997, 41 (02) :251-260

[7]

GAY JD, 1985, ACTA CYTOL, V29, P1043

[8] Quality assurance in cervical cytology screening - Comparison of rapid rescreening and the PAPNET testing system [J].

Halford, JA ;

Wright, RG ;

Ditchmen, EJ .

ACTA CYTOLOGICA, 1997, 41 (01) :79-81

[9]

Hutchinson ML, 1996, ACTA CYTOL, V40, P4

[10] An assessment of partial rescreening as an internal quality control method for cervical smears [J].

Johnson, SJ ;

Hair, T ;

Gibson, L ;

Ridley, B ;

Wadehra, V .

CYTOPATHOLOGY, 1995, 6 (06) :376-387

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