Synthesis, characterization and electrochemical studies on the interaction mechanism between copper(II) complex and DNA

被引：0

作者：

Zhang, Xiu Ling ^{[1
]}

Guo, Feng ^{[1
]}

机构：

[1] DeZhou Univ, Dept Chem, Dezhou 253023, Peoples R China

来源：

ASIAN JOURNAL OF CHEMISTRY | 2008年 / 20卷 / 08期

关键词：

Schiff base; cyclic voltammetry; copper(II) complex; DNA;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Cu(II) Schiff base was synthesized and characterized by elemental analysis, molar conductivity, IR and thermal decomposition. Cyclic voltammetry was used to investigate the interaction between [Cu(GNA)(H2O)]center dot H2O (where GNA = glycine) and DNA. The complex had excellent electrochemical activity on the glassy carbon electrode (GCE) with a couple quasi-reversible redox peaks. In 0.05 M Britton-Robinson (B-R) buffer solution (pH 4.86), the binding ratio between [Cu(GNA) (H2O)]center dot H2O and DNA was found to be 1:1 and the binding constant was 1.67 x 10(4) L mol(-1).

引用

页码：6269 / 6275

页数：7

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