Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution

被引：76

作者：

Hou, Xianfeng ^{[1
]}

Yu, Qingxiang ^{[1
]}

Zeng, Fang ^{[1
]}

Yu, Changmin ^{[1
]}

Wu, Shuizhu ^{[1
]}

机构：

[1] S China Univ Technol, State Key Lab Luminescent Mat & Devices, Coll Mat Sci & Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 26期

关键词：

HYDROGEN-PEROXIDE; TURN-ON; PROBES; NANOPARTICLES; SENSORS; TRANSFERASE; CADMIUM; EXCIMER; SULFIDE; CATION;

D O I：

10.1039/c4cc00473f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first ratiometric fluorescent probe for gamma-glutamyltranspeptidase (GGT) was developed, which functions through GGT-induced variation of substitution and subsequent changes in photophysical properties. It can detect GGT in human serum, and be used to visualize the endogenous GGT in ovarian cancer cells.

引用

页码：3417 / 3420

页数：4

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