Antioxidant effects of L-carnosine on liposomes and beef homogenates

被引:38
作者
Lee, BJ [1 ]
Hendricks, DG [1 ]
机构
[1] UTAH STATE UNIV,DEPT NUTR & FOOD SCI,LOGAN,UT 84322
关键词
carnosine; antioxidant; deoxyribose; lipid peroxidation; ground beef;
D O I
10.1111/j.1365-2621.1997.tb15009.x
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The antioxidant activity of carnosine (beta-alanylhistidine dipeptide) was investigated using several systems. In the presence of 100 mu M ascorbic acid, carnosine inhibited metal ion-catalyzed deoxyribose degradation in a dose-dependent manner, indicating its hydroxyl radical-scavenging activity. Carnosine strongly inhibited metal ion-catalyzed liposomal lipid peroxidation in the presence of 100 mu M ascorbic acid or 100 mu M H2O2. Carnosine also inhibited thiobarbituric acid-reactive substances (TBARS) formation from ground beef homogenates. An increase in TBARS formation was caused by addition of 10 ppm Fe2+ to the homogenates. Carnosine presence prevented such increase and it may be useful as an adjunct against oxidative tissue damage or for increasing shelf life.
引用
收藏
页码:931 / &
页数:5
相关论文
共 48 条
[1]   LIPID OXIDATION AND COLOR STABILITY IN RESTRUCTURED MEAT SYSTEMS DURING FROZEN STORAGE [J].
AKAMITTATH, JG ;
BREKKE, CJ ;
SCHANUS, EG .
JOURNAL OF FOOD SCIENCE, 1990, 55 (06) :1513-1517
[2]  
ARUOMA OI, 1994, METHOD ENZYMOL, V233, P57
[3]  
AUST S D, 1985, Journal of Free Radicals in Biology and Medicine, V1, P3, DOI 10.1016/0748-5514(85)90025-X
[4]  
AUST SD, 1989, BIBL NUTR DIET, V43, P266
[5]   L-CARNOSINE (BETA-ALANYL-L-HISTIDINE) AND CARCININE (BETA-ALANYLHISTAMINE) ACT AS NATURAL ANTIOXIDANTS WITH HYDROXYL-RADICAL-SCAVENGING AND LIPID-PEROXIDASE ACTIVITIES [J].
BABIZHAYEV, MA ;
SEGUIN, MC ;
GUEYNE, J ;
EVSTIGNEEVA, RP ;
AGEYEVA, EA ;
ZHELTUKHINA, GA .
BIOCHEMICAL JOURNAL, 1994, 304 :509-516
[6]   BIOSYNTHESIS OF CARNOSINE AND RELATED PEPTIDES BY SKELETAL-MUSCLE CELLS IN PRIMARY CULTURE [J].
BAUER, K ;
SCHULZ, M .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1994, 219 (1-2) :43-47
[7]  
BOLDYREV AA, 1987, BIOCHEM INT, V15, P1105
[8]  
BOLDYREV AA, 1990, ADV ENZYME REGUL, V30, P175
[10]  
Buege J A, 1978, Methods Enzymol, V52, P302