Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer

被引:28
作者
Alfarone, Andrea
Panebianco, Valeria [2 ]
Schillaci, Orazio [3 ,4 ]
Salciccia, Stefano
Cattarino, Susanna
Mariotti, Gianna
Gentilucci, Alessandro
Von Heland, Magnus
Passariello, Roberto [2 ]
Gentile, Vincenzo
Sciarra, Alessandro [1 ,5 ,6 ,7 ,8 ]
机构
[1] Univ Roma La Sapienza, Prostate Canc Unit, Dept Urol, Policlin Umberto 1, I-00161 Rome, Italy
[2] Univ Roma La Sapienza, Dept Radiol, I-00161 Rome, Italy
[3] Univ Roma Tor Vergata, Dept Biopathol & Diagnost Imaging, Pozzilli, Italy
[4] IRCCS Neuromed, Pozzilli, Italy
[5] Univ Roma La Sapienza, Dept Urol U Bracci, I-00161 Rome, Italy
[6] Univ Roma La Sapienza, Sch Med, I-00161 Rome, Italy
[7] Univ Roma La Sapienza, Sch Urol, I-00161 Rome, Italy
[8] Univ Roma La Sapienza, Sch Nephrol, I-00161 Rome, Italy
关键词
Prostate neoplasm; Local recurrence; Radical prostatectomy; Imaging; BIOCHEMICAL FAILURE; ANTIGEN RECURRENCE; PSA; TOMOGRAPHY; PROGRESSION; THERAPY; RELAPSE; RADIOTHERAPY; KINETICS; CHOLINE;
D O I
10.1016/j.critrevonc.2012.01.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: Our aim was to assess whether multiparametric magnetic resonance and PET-CT can have a role in detecting local recurrence in patients with biochemical recurrence after radical prostatectomy. Methods: We reviewed the recent international literature by carrying out a PUBMED search. Results: We critically reviewed 11 recent original studies about the use of PET-CT and 5 recent studies about the use of multiparametric magnetic resonance. PET-CT has not shown significant results in terms of detection rate for local recurrence in patients with low level of PSA. Multiparametric magnetic resonance showed encouraging results to detect local recurrence in patients with low PSA and with small diameter lesions. Conclusions: Currently, most important urological societies do not consider multiparametric magnetic resonance and PET-CT in the follow-up of patients with suspected local recurrence after radical prostatectomy. We can assert that multiparametric magnetic resonance seems to have excellent results in detecting local recurrence in patients submitted to radical prostatectomy and PSA < 1.5 ng/ml. (c) 2012 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:109 / 121
页数:13
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