Acute Ataxia in Children: Approach to Clinical Presentation and Role of Additional Investigations

被引:39
作者
Poretti, Andrea [1 ,2 ]
Benson, Jane E. [1 ]
Huisman, Thierry A. G. M. [1 ]
Boltshauser, Eugen [2 ]
机构
[1] Johns Hopkins Univ, Sch Med, Div Pediat Radiol, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA
[2] Univ Childrens Hosp Zurich, Dept Pediat Neurol, Zurich, Switzerland
关键词
acute ataxia; children; differential diagnosis; cerebellar ataxia; neuroimaging; acute cerebellitis; OPSOCLONUS-MYOCLONUS SYNDROME; ACUTE DISSEMINATED ENCEPHALOMYELITIS; GUILLAIN-BARRE-SYNDROME; PEDIATRIC MULTIPLE-SCLEROSIS; ACUTE CEREBELLAR-ATAXIA; SYRUP-URINE-DISEASE; PSYCHOGENIC MOVEMENT-DISORDERS; PYRUVATE-DEHYDROGENASE COMPLEX; VERTEBRAL ARTERY DISSECTION; BENIGN PAROXYSMAL VERTIGO;
D O I
10.1055/s-0032-1329909
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Acute ataxia is a fairly common emergency that confronts the pediatric neurologist in daily life. The differential diagnosis of acute pediatric ataxia is wide, but informed history and careful clinical examination can narrow it and help target investigations. This review discusses various etiologies of acute pediatric ataxia, focusing on clinical presentation, diagnostic considerations, and approach to investigation. Aspects of treatment and prognosis are also mentioned. Diseases with potentially high morbidity and mortality, such as acute cerebellitis, opsoclonus-myoclonus syndrome, and cerebellar stroke, receive particular attention.
引用
收藏
页码:127 / 141
页数:15
相关论文
共 139 条
[1]   Traumatic bilateral vertebral artery dissection at the dural entry point site in a 10-year-old boy [J].
Adaletli, I ;
Sirikci, A ;
Ulus, S ;
Yilmaz, MH ;
Kervancioglu, S ;
Kurugoglu, S .
PEDIATRIC SURGERY INTERNATIONAL, 2006, 22 (05) :468-470
[2]   Psychogenic and organic movement disorders in children [J].
Ahmed, M. A. S. ;
Martinez, Adelaida ;
Yee, Ayeaye ;
Cahill, Denise ;
Besag, Frank M. C. .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2008, 50 (04) :300-304
[3]   Neurologic Manifestations of Varicella Zoster Virus Infections [J].
Amlie-Lefond, Catherine ;
Jubelt, Burk .
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2009, 9 (06) :430-434
[4]   Etiology of vertigo in children [J].
Balatsouras, Dimitrios G. ;
Kaberos, Antonis ;
Assimakopoulos, Dimitrios ;
Katotomichelakis, Michael ;
Economou, Nicolas C. ;
Korres, Stavros G. .
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2007, 71 (03) :487-494
[5]   MRI features of pediatric multiple sclerosis [J].
Banwell, B. ;
Shroff, M. ;
Ness, J. M. ;
Jeffery, D. ;
Schwid, S. ;
Weinstock-Guttman, B. .
NEUROLOGY, 2007, 68 :S46-S53
[6]   Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions [J].
Banwell, Brenda ;
Ghezzi, Angelo ;
Bar-Or, Amit ;
Mikaeloff, Yann ;
Tardieu, Marc .
LANCET NEUROLOGY, 2007, 6 (10) :887-902
[7]   Pyruvate dehydrogenase complex deficiency: four neurological phenotypes with differing pathogenesis [J].
Barnerias, Christine ;
Saudubray, Jean-Marie ;
Touati, Guy ;
De Lonlay, Pascale ;
Dulac, Olivier ;
Ponsot, Gerard ;
Marsac, Cecile ;
Brivet, Michele ;
Desguerre, Isabelle .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2010, 52 (02) :e1-e9
[8]   Response to rituximab in 3 children with opsoclonus-myoclonus syndrome resistant to conventional treatments [J].
Battaglia, Teresa ;
De Grandis, Elisa ;
Mirabelli-Badenier, Marisol ;
Boeri, Luca ;
Morcaldi, Guido ;
Barabino, Paola ;
Intra, Chiara ;
Naselli, Francesca ;
Pistoia, Vito ;
Veneselli, Edvige ;
Conte, Massimo .
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2012, 16 (02) :192-195
[9]  
Baxter PS., 2012, CEREBELLAR DISORDERS, P361
[10]   Response to rituximab in a child with neuroblastoma and opsoclonus-myoclonus [J].
Bell, Jessica ;
Moran, Cassandra ;
Blatt, Julie .
PEDIATRIC BLOOD & CANCER, 2008, 50 (02) :370-371