TARGETED THERAPIES Pazopanib for soft-tissue sarcoma: a PALETTE of data emerges

被引：6

作者：

Ray-Coquard, Isabelle ^{[1
]}

Thomas, David ^{[2
,3
]}

机构：

[1] Leon Berard Canc Ctr, Dept Adult Med Oncol, F-69008 Lyon, France

[2] Univ Melbourne, Dept Canc Med, Peter MacCallum Canc Ctr, Melbourne, Vic 3002, Australia

[3] Univ Melbourne, Div Res, Peter MacCallum Canc Ctr, Melbourne, Vic 3002, Australia

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2012年 / 9卷 / 08期

关键词：

RANDOMIZED PHASE-II; EUROPEAN ORGANIZATION; CANCER; ANGIOGENESIS; GEMCITABINE; EORTC;

D O I：

10.1038/nrclinonc.2012.113

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The PALETTE randomized phase III trial has reported a statistically significant benefit for the use of pazopanib compared to placebo in terms of progression-free survival for the treatment of soft-tissue sarcoma. However, no benefit in terms of overall survival was observed, the reasons for which might lie in the study design. Ray-Coquard, I. & Thomas, D. Nat. Rev. Clin. Oncol. 9, 431-432 (2012); published online 3 July 2012; doi:10.1038/nrclinonc.2012.113

引用

页码：431 / 432

页数：2

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