The psychopathological spectrum of Gilles de la Tourette syndrome

被引:80
作者
Cavanna, Andrea E. [1 ,2 ,3 ]
Rickards, Hugh [1 ,2 ]
机构
[1] Barberry Natl Ctr Mental Hlth, Dept Neuropsychiat, Birmingham B15 2FG, W Midlands, England
[2] BSMHFT, Birmingham, W Midlands, England
[3] UCL, Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London, England
关键词
Gilles de la Tourette syndrome; Tics; Behaviour; Coprophenomena; Echophenomena; Paliphenomena; Obsessive-compulsive symptoms; Obsessive-compulsive disorder; Attention-deficit and hyperactivity disorder; Affective disorders; Impulse control disorders; EUROPEAN CLINICAL GUIDELINES; OBSESSIVE-COMPULSIVE DISORDER; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT HYPERACTIVITY DISORDER; IMPULSE-CONTROL DISORDERS; QUALITY-OF-LIFE; TIC DISORDERS; BRAIN-STIMULATION; BASAL GANGLIA; REPETITIVE BEHAVIOR;
D O I
10.1016/j.neubiorev.2012.10.011
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Gilles de la Tourette syndrome (GTS) holds a unique status as quintessentially neuropsychiatric condition at the interface between neurology (movement disorder) and psychiatry (behavioural condition). This is a reflection of the common observation that the vast majority of patients present with behavioural problems in association with the motor and vocal tics which define GTS. The present article focuses on the relationship between GTS and obsessive-compulsive disorder (OCD), attention-deficit and hyperactivity disorder (ADHD), affective disorders (both major depression and bipolar affective disorder), and personality disorders. Over the last decade, converging lines of research have pointed towards the concept of a 'GTS spectrum', encompassing motor phenomena and behavioural symptoms, with important implications for the clinical management of patients. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1008 / 1015
页数:8
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