A human telomeric DNA-based chiral biosensor

被引：23
作者：
Feng, Lingyan [1 ]
Xu, Bailu [1 ]
Ren, Jinsong [1 ]
Zhao, Chuanqi [1 ]
Qu, Xiaogang [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, Grad Sch, Lab Chem Biol,Div Biol Inorgan Chem,State Key Lab, Changchun 130022, Jilin, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 72期
关键词：
WALLED CARBON NANOTUBES; QUADRUPLEX DNA; BINDING; REAGENTLESS; SEQUENCE; TARGET; SENSOR; ACIDS;
D O I：
10.1039/c2cc34776h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Here we report an electrochemical DNA (E-DNA) chiral sensor that can distinguish zinc-finger like metallo-supramolecular enantiomers based on human telomeric G-quadruplex formation specifically induced by one of the enantiomers. The assay is easy to operate and reusable with an enantioselective recognition ratio higher than 5.
引用
收藏
页码：9068 / 9070
页数：3
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