Photomodulation of Fluorescent Upconverting Nanoparticle Markers in Live Organisms by Using Molecular Switches

被引:62
作者
Boyer, John-Christopher [2 ,3 ]
Carling, Carl-Johan [2 ,3 ]
Chua, Shu Yi [1 ]
Wilson, Danielle [2 ,3 ]
Johnsen, Bob [1 ]
Baillie, David [1 ]
Branda, Neil R. [2 ,3 ]
机构
[1] Simon Fraser Univ, Dept Mol Biol & Biochem, Burnaby, BC V5A 1S6, Canada
[2] Simon Fraser Univ, Dept Chem, Burnaby, BC V5A 1S6, Canada
[3] Simon Fraser Univ, LABS 4D, Burnaby, BC V5A 1S6, Canada
基金
加拿大创新基金会; 加拿大自然科学与工程研究理事会;
关键词
fluorescence imaging; nanoparticles; optical probes; upconversion; NEAR-INFRARED LIGHT; NANOCRYSTALS;
D O I
10.1002/chem.201103767
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In vivo upconversion: Photoresponsive dithienylethene ligands decorated onto lanthanide-doped, upconverting nanoparticles are used to modulate the amount of emission from the nanoparticles. The hybrid system can be toggled between 'bright' and 'dark' states by using two different types of light in living nematodes (see figure). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:3122 / 3126
页数:5
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