Human coronavirus NL63 in hospitalized children with respiratory infection: A 2-year study from Chongqing, China

被引:3
作者
Xin, Chen [1 ]
Yong, Zhang Zhi [1 ]
Yan, Li [2 ]
Dong, Zhao Xiao [1 ]
机构
[1] Chongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R China
[2] Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB, Canada
基金
中国国家自然科学基金;
关键词
Acute lower respiratory tract infections; Epidemiology; HCoV-NL63; Respiratory tract virus; HUMAN METAPNEUMOVIRUS; TRACT INFECTIONS; DISEASE; INFANTS;
D O I
10.1007/s13312-012-0194-1
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Human coronavirus (HCoV) NL63, a newly discovered coronavirus, has been associated with acute lower respiratory tract infections (ALRTI). We detected HCoV-NL63 via reverse transcriptional PCR (RT-PCR) in eight out of 878 respiratory specimens freshly collected from hospitalized children with ALRTI between April 2006 and March 2008 in Children's Hospital of Chongqing Medical University. Peak of HCoV-NL63 activity often appeared during the summer and autumn in Chongqing area. All children with HCoV-NL63 infection were < 1 year of age. The diagnosis included bronchial pneumonia, bronchitis, interstitial pneumonia and bronchiolitis. All children recovered.
引用
收藏
页码:825 / 828
页数:4
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