Human coronavirus NL63 in hospitalized children with respiratory infection: A 2-year study from Chongqing, China
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作者:
Xin, Chen
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Chongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R ChinaChongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R China
Xin, Chen
[1
]
Yong, Zhang Zhi
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Chongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R ChinaChongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R China
Yong, Zhang Zhi
[1
]
Yan, Li
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Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB, CanadaChongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R China
Yan, Li
[2
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Dong, Zhao Xiao
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Chongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R ChinaChongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R China
Dong, Zhao Xiao
[1
]
机构:
[1] Chongqing Med Univ, Childrens Hosp, Div Nephrol & Immunol, Chongqing 400014, Peoples R China
Human coronavirus (HCoV) NL63, a newly discovered coronavirus, has been associated with acute lower respiratory tract infections (ALRTI). We detected HCoV-NL63 via reverse transcriptional PCR (RT-PCR) in eight out of 878 respiratory specimens freshly collected from hospitalized children with ALRTI between April 2006 and March 2008 in Children's Hospital of Chongqing Medical University. Peak of HCoV-NL63 activity often appeared during the summer and autumn in Chongqing area. All children with HCoV-NL63 infection were < 1 year of age. The diagnosis included bronchial pneumonia, bronchitis, interstitial pneumonia and bronchiolitis. All children recovered.