The Current Drug Treatment Landscape for Diabetes and Perspectives for the Future

被引:70
|
作者
Bailey, C. J. [1 ]
机构
[1] Aston Univ, Sch Life & Hlth Sci, Birmingham B4 7ET, W Midlands, England
关键词
GLP-1 RECEPTOR AGONISTS; TYPE-2; INHIBITORS; THERAPY; MANAGEMENT; METFORMIN; OBESITY; PATHOPHYSIOLOGY; ASSOCIATION; EFFICACY;
D O I
10.1002/cpt.144
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The escalating global epidemic of type 2 diabetes mellitus has focused attention on the devastating consequences of protracted hyperglycemia. Early and effective intervention to control blood glucose is a fundamental principle of treatment guidelines, requiring assiduous use of current therapies. However, many patients do not achieve or maintain glycemic targets, emphasizing the need for further therapies. This narrative review assesses the available medicinal options to address hyperglycemia and the opportunities to develop novel agents.
引用
收藏
页码:170 / 184
页数:15
相关论文
共 50 条
  • [1] Advanced gastric cancer: Current treatment landscape and future perspectives
    Digklia, Antonia
    Wagner, Anna Dorothea
    WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (08) : 2403 - 2414
  • [2] Advanced gastric cancer:Current treatment landscape and future perspectives
    Antonia Digklia
    Anna Dorothea Wagner
    World Journal of Gastroenterology, 2016, (08) : 2403 - 2414
  • [3] The role of nanotechnology in diabetes treatment: current and future perspectives
    Samuel, Dennis
    Bharali, Dhruba
    Mousa, Shaker A.
    INTERNATIONAL JOURNAL OF NANOTECHNOLOGY, 2011, 8 (1-2) : 53 - 65
  • [4] Neuropsychiatric drug development: Perspectives on the current landscape, opportunities and potential future directions
    Loiodice, Simon
    D'Acquisto, Fulvio
    Drinkenburg, Pim
    Suojanen, Christian
    Llorca, Pierre-Michel
    Manji, Husseini K.
    DRUG DISCOVERY TODAY, 2025, 30 (01)
  • [5] Percutaneous Treatment Approaches in Atrial Fibrillation: Current Landscape and Future Perspectives
    Theofilis, Panagiotis
    Oikonomou, Evangelos
    Antonopoulos, Alexios S.
    Siasos, Gerasimos
    Tsioufis, Konstantinos
    Tousoulis, Dimitris
    BIOMEDICINES, 2022, 10 (09)
  • [6] Metastatic soft tissue sarcoma: current treatment landscape and future perspectives
    Skafida, E.
    Kokkali, S.
    Nikolaou, M.
    Digklia, A.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2017, 17 (06) : 537 - 543
  • [7] Microbiota Transplant in the Treatment of Obesity and Diabetes: Current and Future Perspectives
    Napolitano, Michael
    Covasa, Mihai
    FRONTIERS IN MICROBIOLOGY, 2020, 11
  • [8] Antiepileptic drug treatment 2011; current limitations and future perspectives
    Boon, Paul A. J. M.
    SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2011, 20 (05): : 357 - 358
  • [9] Evolving treatment landscape of immunotherapy in breast cancer: current issues and future perspectives
    Valenza, Carmine
    Rizzo, Graziella
    Passalacqua, Maria Ilenia
    Boldrini, Laura
    Corti, Chiara
    Trapani, Dario
    Curigliano, Giuseppe
    THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2023, 15