Blastocystis: getting to grips with our guileful guest

被引：102
作者：
Scanlan, Pauline D. [1 ]
Stensvold, Christen R. [2 ]
机构：
[1] Natl Univ Ireland Univ Coll Cork, Alimentary Pharmabiot Ctr, Biosci Inst, Cork, Ireland
[2] Statens Serum Inst, Parasitol Lab, Dept Microbiol & Infect Control, DK-2300 Copenhagen S, Denmark
来源：
TRENDS IN PARASITOLOGY | 2013年 / 29卷 / 11期
关键词：
Blastoeystis; genomics; virulence; coevolution; microbiota; hygiene hypothesis; INFLAMMATORY-BOWEL-DISEASE; VIRUS-LIKE PARTICLES; GUT MICROBIOTA; ULCERATIVE-COLITIS; ENTAMOEBA-HISTOLYTICA; INDEPENDENT ANALYSIS; COLORECTAL-CANCER; GENETIC DIVERSITY; EPITHELIAL-CELLS; INFECTION;
D O I：
10.1016/j.pt.2013.08.006
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Blastocystis, a common single-celled intestinal parasite of humans and animals, continues to puzzle clinical microbiologists, gastroenterologists, and general practitioners who are still unsure of the clinical significance of the organism. Here we consider some less well-addressed areas of Blastocystis research, which, facilitated by recent technological advances, could potentially turn out to be significant pathways to knowledge. First and foremost we discuss new trends in Blastocystis research, including the 'omics' perspectives, and then highlight some aspects of Blastocystis research in the context of host coevolution, its potential as a biomarker of intestinal functionality, and its relationship to other components of the human intestinal microbiota.
引用
收藏
页码：523 / 529
页数：7
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