Background and study aims: A standard treatment for esophageal squamous cell carcinoma (SCC) with submucosal invasion is considered to be radical resection at present. In this study, we evaluated the efficacy of multimodality treatments with endoscopic mucosal resection (EMR) of esophageal SCC with submucosal invasion. Method: Eighteen cases of SCC with submucosal invasion were treated with EMR. Lymphatic invasion was found in 11 cases (67%), and there were no cases of blood vessel invasion. EMR was performed prior to any other treatment. Chemotherapy and/or radiotherapy were added if indicated by the histopathological features. Results: There were no cases of local recurrence. Lymph-node recurrence was detected in I case treated with EMR alone. There were no cases of cancer death. The overall survival rate was 83% in all patients. Conclusions: Multimodality treatments with EMR were effective in treating esophageal SCC with submucosal invasion.
机构:
Natl Canc Ctr, Endoscopy Div, Tokyo, Japan
Fukushima Med Univ, Sch Med, Dept Gastroenterol, Fukushima, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Kawashima, Kazumasa
Abe, Seiichiro
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Natl Canc Ctr, Endoscopy Div, Tokyo, Japan
Natl Canc Ctr, Endoscopy Div, 5-1-1 Tsukiji,Chuo Ku, Tokyo 1040045, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Abe, Seiichiro
Koga, Masakazu
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Natl Canc Ctr, Endoscopy Div, Tokyo, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Koga, Masakazu
Nonaka, Satoru
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Natl Canc Ctr, Endoscopy Div, Tokyo, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Nonaka, Satoru
Suzuki, Haruhisa
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Natl Canc Ctr, Endoscopy Div, Tokyo, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Suzuki, Haruhisa
Yoshinaga, Shigetaka
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Natl Canc Ctr, Endoscopy Div, Tokyo, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Yoshinaga, Shigetaka
Oda, Ichiro
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Natl Canc Ctr, Endoscopy Div, Tokyo, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Oda, Ichiro
Hikichi, Takuto
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机构:
Natl Canc Ctr, Endoscopy Div, Tokyo, Japan
Fukushima Med Univ Hosp, Dept Endoscopy, Fukushima, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Hikichi, Takuto
Ohira, Hiromasa
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Fukushima Med Univ, Sch Med, Dept Gastroenterol, Fukushima, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
Ohira, Hiromasa
Saito, Yutaka
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Natl Canc Ctr, Endoscopy Div, Tokyo, JapanNatl Canc Ctr, Endoscopy Div, Tokyo, Japan
机构:
Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Second Mil Med Univ, Dept Clin Med, Shanghai, Peoples R ChinaSecond Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Li, Ju-Dong
Xu, Xin-Fei
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Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Second Mil Med Univ, Dept Clin Med, Shanghai, Peoples R ChinaSecond Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Xu, Xin-Fei
Yu, Jiong-Jie
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Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Second Mil Med Univ, Dept Clin Med, Shanghai, Peoples R ChinaSecond Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Yu, Jiong-Jie
Sun, Li-Yang
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机构:
Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Second Mil Med Univ, Dept Clin Med, Shanghai, Peoples R ChinaSecond Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Sun, Li-Yang
Wang, Zheng
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机构:
Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
Second Mil Med Univ, Dept Clin Med, Shanghai, Peoples R ChinaSecond Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepatobiliary Surg, 225 Changhai Rd, Shanghai 200438, Peoples R China
机构:
Shiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, JapanShiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, Japan
Mochizuki, Yosuke
Saito, Yasuharu
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机构:
Shiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, JapanShiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, Japan
Saito, Yasuharu
Tsujikawa, Tomoyuki
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机构:
Shiga Univ Med Sci, Dept Med, Otsu, Shiga 5202192, JapanShiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, Japan
Tsujikawa, Tomoyuki
Fujiyama, Yoshihide
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机构:
Shiga Univ Med Sci, Dept Med, Otsu, Shiga 5202192, JapanShiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, Japan
Fujiyama, Yoshihide
Andoh, Akira
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机构:
Shiga Univ Med Sci, Div Mucosal Immunol, Grad Sch Med, Otsu, Shiga 5202192, JapanShiga Univ Med Sci, Div Digest Endoscopy, Otsu, Shiga 5202192, Japan