Quantitative Imaging of Bilirubin by Photoacoustic Microscopy

被引：1

作者：

Zhou, Yong ^{[1
]}

Zhang, Chi ^{[1
]}

Yao, Da-Kang ^{[1
]}

Wang, Lihong V. ^{[1
]}

机构：

[1] Washington Univ, Opt Imaging Lab, Dept Biomed Engn, St Louis, MO 63130 USA

来源：

PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2013 | 2013年 / 8581卷

关键词：

photoacoustic microscopy; photoacoustic spectroscopy; bilirubin; scattering medium; RESOLUTION; SKIN;

D O I：

10.1117/12.2004394

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Noninvasive detection of both bilirubin concentration and its distribution is important for disease diagnosis. Here we implemented photoacoustic microscopy (PAM) to detect bilirubin distribution. We first demonstrate that our PAM system can measure the absorption spectra of bilirubin and blood. We also image bilirubin distributions in tissue-mimicking samples, both without and with blood mixed. Our results show that PAM has the potential to quantitatively image bilirubin in vivo for clinical applications.

引用

页数：6

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