Effects of Bronchoscopic Lung Volume Reduction Coil Treatment on Arterial Blood Gases

被引:4
作者
Guelsen, Askin [1 ]
机构
[1] ARCN, Res Ctr Borstel, Div Clin & Mol Allergol, Borstel, Germany
关键词
respiratory failure; bronchoscopic lung volume reduction; coil; emphysema; blood gase; SEVERE EMPHYSEMA; SURGERY; COPD;
D O I
10.1097/LBR.0000000000000529
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background: Bronchoscopic lung volume reduction (BLVR) coil treatment is an increasingly used treatment modality for selected severe emphysema patients in recent years. Emphysema causes dynamic hyperinflation, loss of elastic recoil, air trapping, and decreased exercise capacity in advanced stages. This process progresses over time, leading to hypoxic and hypercapnic respiratory failure. The goal of this study is to elucidate the effects of BLVR coil treatment on arterial blood gas parameters in severe emphysema patients with respiratory failure. Methods: This is a retrospective study performed at a single pneumology center in Turkey. In total, this study included 39 patients diagnosed with severe emphysema who underwent bilateral BLVR coil treatment according to the general inclusion and exclusion criteria in the literature. The patients baseline and 12-month data were collected from medical records. Results: Twelve months after BLVR coil treatment, significant improvements were observed in patients' pulmonary function tests, an increase in partial pressure of oxygen in arterial blood (PaO2) from 58.05 +/- 9.36 to 73.82 +/- 13.3 (P<0.000) and decrease in partial pressure of carbon dioxide in arterial blood (PaCO2) of hypercapnic patients (from 51.60 +/- 4.1 to 46.55 +/- 6.6 mm Hg; P=0.001). Conclusion: BLVR coil treatment is reliable and effective in emphysema patients who have hypoxic or mild hypercapnic respiratory failure. Besides improving lung function, BLVR coil treatment can significantly increase PaO2 and decrease PaCO2 in the medium term.
引用
收藏
页码:90 / 95
页数:6
相关论文
共 21 条
[1]  
[Anonymous], 2018, Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease
[2]   Long-term outcome of bilateral lung volume reduction in 250 consecutive patients with emphysema [J].
Ciccone, AM ;
Meyers, BF ;
Guthrie, TJ ;
Davis, GE ;
Yusen, RD ;
Lefrak, SS ;
Patterson, GA ;
Cooper, JD .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2003, 125 (03) :513-525
[3]   The National Emphysema Treatment Trial (NETT) Part II: Lessons Learned about Lung Volume Reduction Surgery [J].
Criner, Gerard J. ;
Cordova, Francis ;
Sternberg, Alice L. ;
Martinez, Fernando J. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 184 (08) :881-893
[4]   Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema The REVOLENS Randomized Clinical Trial [J].
Deslee, Gaetan ;
Mal, Herve ;
Dutau, Herve ;
Bourdin, Arnaud ;
Vergnon, Jean Michel ;
Pison, Christophe ;
Kessler, Romain ;
Jounieaux, Vincent ;
Thiberville, Luc ;
Leroy, Sylvie ;
Marceau, Armelle ;
Laroumagne, Sophie ;
Mallet, Jean Pierre ;
Dukic, Sylvain ;
Barbe, Coralie ;
Bulsei, Julie ;
Jolly, Damien ;
Durand-Zaleski, Isabelle ;
Marquette, Charles Hugo .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2016, 315 (02) :175-184
[5]  
Fishman A, 2003, NEW ENGL J MED, V348, P2059
[6]   Evaluation of bronchoscopic lung volume reduction coil treatment results in patients with severe emphysema [J].
Gulsen, Askin ;
Sever, Fidan ;
Girgin, Pelin ;
Tamci, Necdet Batuhan ;
Yilmaz, Hatice .
CLINICAL RESPIRATORY JOURNAL, 2017, 11 (05) :585-592
[7]   Patient-specific goals significantly improve after endobronchial coil treatment in patients with severe emphysema [J].
Hartman, Jorine E. ;
Klooster, Karin ;
ten Hacken, Nick H. T. ;
Slebos, Dirk-Jan .
CLINICAL RESPIRATORY JOURNAL, 2018, 12 (06) :2157-2158
[8]   Endoscopic Lung Volume Reduction: An Expert Panel Recommendation - Update 2017 [J].
Herth, Felix J. F. ;
Slebos, Dirk-Jan ;
Criner, Gerard J. ;
Shah, Pallav L. .
RESPIRATION, 2017, 94 (04) :380-388
[9]   Efficacy of long-term noninvasive positive pressure ventilation in stable hypercapnic COPD patients with respiratory failure: a meta-analysis of randomized controlled trials [J].
Liao, Hao ;
Pei, Wendi ;
Li, Hongfu ;
Luo, Yuwen ;
Wang, Kai ;
Li, Rui ;
Xu, Limei ;
Chen, Xin .
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2017, 12 :2977-2984
[10]   Multicentre European study for the treatment of advanced emphysema with bronchial valves [J].
Ninane, Vincent ;
Geltner, Christian ;
Bezzi, Michela ;
Foccoli, Pierfranco ;
Gottlieb, Jens ;
Welte, Tobias ;
Seijo, Luis ;
Zulueta, Javier J. ;
Munavvar, Mohammed ;
Rosell, Antoni ;
Lopez, Marta ;
Jones, Paul W. ;
Coxson, Harvey O. ;
Springmeyer, Steven C. ;
Gonzalez, Xavier .
EUROPEAN RESPIRATORY JOURNAL, 2012, 39 (06) :1319-1325