Fertilization and embryo cleavage after intracytoplasmic spermatid injection in an obstructive azoospermic patient with defective spermiogenesis

被引：22

作者：

Chen, SU

Ho, HN

Chen, HF

Tsai, TC

Lee, TY

Yang, YS

机构：

[1] NATL TAIWAN UNIV HOSP,DEPT OBSTET & GYNECOL,TAIPEI,TAIWAN

[2] NATL TAIWAN UNIV,COLL MED,TAIPEI 10764,TAIWAN

来源：

FERTILITY AND STERILITY | 1996年 / 66卷 / 01期

关键词：

intracytoplasmic spermatid injection; obstructive azoospermia; defective spermiogenesis;

D O I：

10.1016/S0015-0282(16)58406-4

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. Design: Clinical trial. Setting: Reproductive unit of a university teaching hospital. Patient: A patient of obstructive azoospermia with defective spermiogenesis. Intervention: Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. Main Outcome Measures: Fertilization and cleavage. Results: Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. Conclusion: Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.

引用

页码：157 / 160

页数：4

共 6 条

[1]

Courot M, 1970, TESTIS, P339

[2] ARE SPERMATID INJECTIONS INTO HUMAN OOCYTES NOW MANDATORY [J].