Regional homogeneity changes in heavy male smokers: a resting-state functional magnetic resonance imaging study

被引：36

作者：

Yu, Rongjun ^{[1
]}

Zhao, Liyan ^{[2
]}

Tian, Jie ^{[3
]}

Qin, Wei ^{[3
]}

Wang, Wei ^{[4
]}

Yuan, Kai ^{[3
]}

Li, Qiang ^{[4
]}

Lu, Lin ^{[2
]}

机构：

[1] S China Normal Univ, Dept Psychol, Guangzhou, Guangdong, Peoples R China

[2] Peking Univ, Natl Inst Drug Dependence, Beijing 100191, Peoples R China

[3] Xidian Univ, Xian, Peoples R China

[4] Fourth Mil Med Univ, Tangdu Hosp, Xian 710032, Peoples R China

来源：

ADDICTION BIOLOGY | 2013年 / 18卷 / 04期

关键词：

Addiction; insula; magnetic resonance imaging; prefrontal cortex; resting state; smoking; CUE REACTIVITY; ADDICTION; DEPENDENCE; SMOKING;

D O I：

10.1111/j.1369-1600.2011.00359.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies have documented declined global cognitive function and abnormal task-related brain activation in chronic cigarette smokers. However, the effects of long-term heavy smoking on task-independent baseline brain activity are still unknown. Here, we used a regional homogeneity (ReHo) method combined with functional magnetic resonance imaging (fMRI) to investigate spontaneous neural activity in the resting state in heavy smokers. Compared with controls, heavy smokers exhibited decreased ReHo in prefrontal regions, as well as increased ReHo in insula and posterior cingulate cortex. Our study may better our understanding of the neurobiological consequences of smoking.

引用

页码：729 / 731

页数：3

共 10 条

[1] Nicotine replacement in abstinent smokers improves cognitive withdrawal symptoms with modulation of resting brain network dynamics [J].

Cole, David M. ;

Beckmann, Christian F. ;

Long, Christopher J. ;

Matthews, Paul M. ;

Durcan, Michael J. ;

Beaver, John D. .

NEUROIMAGE, 2010, 52 (02) :590-599

[2] MEASURING NICOTINE DEPENDENCE - A REVIEW OF THE FAGERSTROM TOLERANCE QUESTIONNAIRE [J].

FAGERSTROM, KO ;

SCHNEIDER, NG .

JOURNAL OF BEHAVIORAL MEDICINE, 1989, 12 (02) :159-182

[3] Association of Nicotine Addiction and Nicotine's Actions With Separate Cingulate Cortex Functional Circuits [J].

Hong, L. Elliot ;

Gu, Hong ;

Yang, Yihong ;

Ross, Thomas J. ;

Salmeron, Betty Jo ;

Buchholz, Brittany ;

Thaker, Gunvant K. ;

Stein, Elliot A. .

ARCHIVES OF GENERAL PSYCHIATRY, 2009, 66 (04) :431-441

[4] Using coherence to measure regional homogeneity of resting-state fMRI signal [J].

Liu, Dongqiang ;

Yan, Chaogan ;

Ren, Juejing ;

Yao, Li ;

Kiviniemi, Vesa J. ;

Zang, Yufeng .

FRONTIERS IN SYSTEMS NEUROSCIENCE, 2010, 4

[5] Projections of global mortality and burden of disease from 2002 to 2030 [J].

Mathers, Colin D. ;

Loncar, Dejan .

PLOS MEDICINE, 2006, 3 (11) :2011-2030

[6] Damage to the insula disrupts addiction to cigarette smoking [J].

Naqvi, Nasir H. ;

Rudrauf, David ;

Damasio, Hanna ;

Bechara, Antoine .

SCIENCE, 2007, 315 (5811) :531-534

[7] Addiction [J].

Robinson, TE ;

Berridge, KC .

ANNUAL REVIEW OF PSYCHOLOGY, 2003, 54 :25-53

[8] Severity of dependence modulates smokers' neuronal cue reactivity and cigarette craving elicited by tobacco advertisement [J].

Vollstaedt-Klein, Sabine ;

Kobiella, Andrea ;

Buehler, Mira ;

Graf, Caroline ;

Fehr, Christoph ;

Mann, Karl ;

Smolka, Michael N. .

ADDICTION BIOLOGY, 2011, 16 (01) :166-175

[9] Regional homogeneity approach to fMRI data analysis [J].

Zang, YF ;

Jiang, TZ ;

Lu, YL ;

He, Y ;

Tian, LX .

NEUROIMAGE, 2004, 22 (01) :394-400

[10] Anatomical differences and network characteristics underlying smoking cue reactivity [J].

Zhang, Xiaochu ;

Salmeron, Betty Jo ;

Ross, Thomas J. ;

Gu, Hong ;

Geng, Xiujuan ;

Yang, Yihong ;

Stein, Elliot A. .

NEUROIMAGE, 2011, 54 (01) :131-141

← 1 →