SYNTHESIS OF AMINOMETHYL DERIVATIVES OF SOPHORICOSIDE

被引：4
|
作者：
Bondarenko, S. P. [1 ]
Frasinyuk, M. S. [2 ]
Khilya, V. P. [3 ]
机构：
[1] Natl Univ Food Technol, UA-01601 Kiev, Ukraine
[2] Natl Acad Sci Ukraine, Inst Bioorgan Chem & Petrochem, UA-02094 Kiev, Ukraine
[3] Taras Shevchenko Kiev Natl Univ, UA-01033 Kiev, Ukraine
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2012年 / 48卷 / 01期
关键词：
isoflavone; sophoricoside; electrophilic substitution; aminomethylation; aminal; NERVOUS SYSTEM STIMULANTS; SOPHORA-JAPONICA; FLAVONOIDS; INHIBITION; ANALOGS;
D O I：
10.1007/s10600-012-0151-2
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Aminomethylation of the natural isoflavonoid sophoricoside (genistein-4-O-beta-D-glucoside) was studied. It was shown that the most convenient method for performing the aminomethylation was the use of aminals. 6,8-bis-Substituted derivatives of sophoricoside were synthesized.
引用
收藏
页码：26 / 29
页数：4
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