SYNTHESIS OF AMINOMETHYL DERIVATIVES OF SOPHORICOSIDE

被引：4

作者：

Bondarenko, S. P. ^{[1
]}

Frasinyuk, M. S. ^{[2
]}

Khilya, V. P. ^{[3
]}

机构：

[1] Natl Univ Food Technol, UA-01601 Kiev, Ukraine

[2] Natl Acad Sci Ukraine, Inst Bioorgan Chem & Petrochem, UA-02094 Kiev, Ukraine

[3] Taras Shevchenko Kiev Natl Univ, UA-01033 Kiev, Ukraine

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2012年 / 48卷 / 01期

关键词：

isoflavone; sophoricoside; electrophilic substitution; aminomethylation; aminal; NERVOUS SYSTEM STIMULANTS; SOPHORA-JAPONICA; FLAVONOIDS; INHIBITION; ANALOGS;

D O I：

10.1007/s10600-012-0151-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Aminomethylation of the natural isoflavonoid sophoricoside (genistein-4-O-beta-D-glucoside) was studied. It was shown that the most convenient method for performing the aminomethylation was the use of aminals. 6,8-bis-Substituted derivatives of sophoricoside were synthesized.

引用

页码：26 / 29

页数：4

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