Genome-wide association study identifies markers associated with carcass and meat quality traits in Italian Large White pigs

被引:15
作者
Fabbri, M. C. [1 ]
Zappaterra, M. [1 ]
Davoli, R. [1 ]
Zambonelli, P. [1 ]
机构
[1] Bologna Univ, Dept Agr & Food Sci DISTAL, Viale G Fanin 46, I-40127 Bologna, Italy
关键词
carcass traits; genetic markers; GWAS; meat quality; swine;
D O I
10.1111/age.13013
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
A GWAS was performed using the genotypes obtained by PorcineSNP60 v2 BeadChip and 11 phenotypic traits (carcass lean meat percentage; backfat thickness; Longissimus thoracis muscle thickness; lightness; backfat thickness measured with caliper at the midline; meat pH measured at about 1 h post mortem and 24 h post mortem; CIEL*,a* andb* color parameters; and water-holding capacity). Three markers were associated with three of the phenotypic traits considered: M1GA0009592 (SSC7) with backfat thickness and lean meat content, DIAS0002910 (SSC6) and ALGA0109856 (SSC6) with water-holding capacity. The marker M1GA0009592, associated with backfat thickness, lies in a QTL region near the geneJARID2, which is a transcription factor also involved in the regulation of adipose-derived stem cell pluripotency. The results seem to indicate a possible role of these genomic regions in the regulation of pig carcass fatness (i.e. backfat at last rib) and water-holding capacity.
引用
收藏
页码:950 / 952
页数:3
相关论文
共 9 条
[1]   Control procedures and estimators of the false discovery rate and their application in low-dimensional settings: an empirical investigation [J].
Brinster, Regina ;
Koettgen, Anna ;
Tayo, Bamidele O. ;
Schumacher, Martin ;
Sekula, Peggy .
BMC BIOINFORMATICS, 2018, 19
[2]  
Ciobanu DC, 2011, GENETICS OF THE PIG, 2ND EDITION, P355, DOI 10.1079/9781845937560.0355
[3]   Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells [J].
Cvoro, Aleksandra ;
Bajic, Aleksander ;
Zhang, Aijun ;
Simon, Marisa ;
Golic, Igor ;
Sieglaff, Douglas H. ;
Maletic-Savatic, Mirjana ;
Korac, Aleksandra ;
Webb, Paul .
PLOS ONE, 2016, 11 (10)
[4]   Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma [J].
Fu, Wenxiang ;
Asp, Patrik ;
Canter, Brian ;
Dynlacht, Brian David .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (25) :9151-9156
[5]   Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB [J].
Hu, Zhi-Liang ;
Park, Carissa A. ;
Reecy, James M. .
NUCLEIC ACIDS RESEARCH, 2019, 47 (D1) :D701-D710
[6]  
Nagamine Y, 2003, GENETICS, V164, P629
[7]   Detection of multiple quantitative trait loci and their pleiotropic effects in outbred pig populations [J].
Nagamine, Yoshitaka ;
Pong-Wong, Ricardo ;
Visscher, Peter M. ;
Haley, Chris S. .
GENETICS SELECTION EVOLUTION, 2009, 41
[8]   Fine mapping and imprinting analysis for fatness trait QTLs in pigs [J].
Rattink, AP ;
De Koning, DJ ;
Faivre, M ;
Harlizius, B ;
van Arendonk, JAM ;
Groenen, MAM .
MAMMALIAN GENOME, 2000, 11 (08) :656-661
[9]   Muscle transcriptome analysis identifies genes involved in ciliogenesis and the molecular cascade associated with intramuscular fat content in Large White heavy pigs [J].
Zappaterra, Martina ;
Gioiosa, Silvia ;
Chillemi, Giovanni ;
Zambonelli, Paolo ;
Davoli, Roberta .
PLOS ONE, 2020, 15 (05)