One-Step Synthesis of 1,2,5-Trisubstituted Pyrroles by Copper Catalyzed Condensation of 1,4-Diones with Primary Amines

被引：9

作者：

Srinivas, Rapelli ^{[1
]}

Thirupathi, Boningari ^{[1
]}

Kumar, J. K. Prashanth ^{[1
]}

Prasad, Avvari N. ^{[1
]}

Reddy, Benjaram M. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Inorgan & Phys Chem Div, Hyderabad 500607, Andhra Pradesh, India

来源：

CURRENT ORGANIC CHEMISTRY | 2012年 / 16卷 / 20期

关键词：

CuI/C; Heterogeneous catalyst; Paal-Knorr condensation; N-Substituted pyrroles; Solvent-free; ONE-POT SYNTHESIS; HETEROGENEOUS CATALYST; SUBSTITUTED PYRROLES; ACTIVATED CARBON; ACETYLACETONATE; NANOPARTICLES; ADSORPTION; CHEMISTRY; PLATINUM; CHLORIDE;

D O I：

10.2174/138527212803520182

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly dispersed copper iodide on activated carbon (CuI/C) solid catalyst has been investigated for the Paal-Knorr condensation of gamma-diketones with aliphatic, aromatic and heterocyclic amines under solvent-free conditions; which lead to the formation of N-substituted pyrrole derivatives in excellent yields. This simple experimental procedure combined with easy recovery and reusability of the catalyst is expected to contribute to the progression of a clean and ecofriendly strategy for the synthesis of N-substituted pyrrole derivatives.

引用

页码：2482 / 2489

页数：8

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