Pityriasis rubra pilaris

被引：6
作者：
Wollina, U. [1 ]
机构：
[1] Tech Univ Dresden, Klin Dermatol & Allergol, Krankenhaus Dresden Friedrichstadt, Stadt Klinikum,Akad Lehrkrankenhaus, D-01067 Dresden, Germany
来源：
HAUTARZT | 2012年 / 63卷 / 08期
关键词：
Pityriasis rubra pilaris; Classification; Histopathology; Comorbidity; Therapy; OF-THE-LITERATURE; SKIN DISEASES; THERAPY; SUPERANTIGENS; ETANERCEPT; ADALIMUMAB; INFLIXIMAB; SERIES; ALPHA;
D O I：
10.1007/s00105-012-2424-x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Pityriasis rubra pilaris is an inflammatory papulosquamous skin disease of unknown etiology. Incidence rates vary between 1:5,000-1:50,000. Six subtypes are differentiated on clinical background. The juvenile circumscribed subtype has best prognosis. Generalized disease impairs quality of life of patients. It is associated with various complications and comorbidities. Treatment of pityriasis rubra pilaris is challenging. Retinoids are first line drugs. In recalcitrant cases, tumor necrosis factor-alpha inhibitors have been used successfully.
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收藏
页码：655 / 661
页数：7
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