Engaging thieno[2,3-b]indole-2,3-dione for the efficient synthesis of spiro[indoline-3,4′-thiopyrano[2,3-b]indole] by reaction withN-substituted isatilidenes

被引：8

作者：

Thomas, Noble V. ^{[1
]}

Sathi, Vidya ^{[1
]}

Deepthi, Ani ^{[1
]}

Sudheendran Leena, Sruthi ^{[1
]}

Chopra, Sidharth ^{[2
]}

机构：

[1] Univ Kerala, Dept Chem, Thiruvananthapuram 695581, Kerala, India

[2] CSIR Cent Drug Res Inst, Div Microbiol, Lucknow, Uttar Pradesh, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2021年 / 58卷 / 01期

关键词：

DERIVATIVES;

D O I：

10.1002/jhet.4147

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient method, proceeding through a new mechanistic pathway, for the synthesis of spiro[indoline-3,4-thiopyrano[2.3-b]indole derivatives have been developed by exploiting the reaction of thieno[2,3-b]indole-2,3-dione with N-substituted isatilidenes. The compounds synthesized have been screened for antibacterial activity. The generality of the reaction and mechanistic rationale are presented.

引用

页码：48 / 55

页数：8

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