Nickel-Catalyzed Regio- and Stereoselective Reductive Coupling between Methylenecyclopropanes, Aldehydes, and Triethylborane with Retention of the Cyclopropane Ring

被引：11

作者：

Ogata, Kenichi ^{[1
]}

Shimada, Daisuke ^{[1
]}

Fukuzawa, Shin-ichi ^{[1
]}

机构：

[1] Chuo Univ, Dept Appl Chem, Inst Sci & Engn, Bunkyo Ku, Tokyo 1128551, Japan

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 20期

关键词：

alkenes; cyclic compound; methylenecyclopropane; nickel; synthetic methods; ETHYL CYCLOPROPYLIDENEACETATE; ENANTIOSELECTIVE SYNTHESIS; 3+2+2 COCYCLIZATION; ALKYNES; LIGAND; CYCLOADDITION; COMPLEXES; ADDITIONS; ALCOHOLS; DIENES;

D O I：

10.1002/chem.201200271

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Running rings: The first regio- and stereoselective reductive coupling between methylenecyclopropanes, aldehydes, and triethylborane with retention of the cyclopropane ring was achieved using a nickel-phosphine catalyst (see scheme). The reductive coupling reaction constructed a stereo-defined cyclopropane ring with formation of a quaternary stereogenic carbon center. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6142 / 6146

页数：5

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