Ruthenium-catalyzed oxidation of alkynes to 1,2-diketones under room temperature and one-pot synthesis of quinoxalines

被引：63
作者：
Xu, Yuan [1 ]
Wan, Xiaobing [1 ]
机构：
[1] Soochow Univ, Key Lab Organ Synth Jiangsu Prov, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Jiangsu, Peoples R China
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Ruthenium; Alkynes; Oxidation; 1,2-Diketones; Quinoxalines; EFFICIENT SYNTHESIS; MOLECULAR-OXYGEN; BOND-CLEAVAGE; DERIVATIVES; DMSO; 1,3-DIKETONES; METHODOLOGY; PALLADIUM; BENZILS; ALKENES;
D O I：
10.1016/j.tetlet.2012.11.142
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A ruthenium-catalyzed alkyne oxidation to 1,2-diketones using Oxone under room temperature is reported. Both substrate scope and mechanism were discussed. Notably, combination of the alkyne oxidation and condensation cyclization in one pot offers a very efficient and convenient entry into quinoxaline derivatives. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：642 / 645
页数：4
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