A review of Omics research in acupuncture: The relevance and future prospects for understanding the nature of meridians and acupoints
被引:36
作者:
Jia, Jun
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机构:
Capital Med Univ, Dept Physiol, Beijing 100069, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Jia, Jun
[2
]
Yu, Yan
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机构:
Capital Med Univ, Dept Physiol, Beijing 100069, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Yu, Yan
[2
]
Deng, Jia-Hui
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机构:
Capital Med Univ, Dept Physiol, Beijing 100069, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Deng, Jia-Hui
[2
]
Robinson, Nicola
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机构:
London S Bank Univ, Fac Hlth & Social Care, London SE1 0AA, EnglandCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Robinson, Nicola
[3
]
Bovey, Mark
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机构:
British Acupuncture Council, London W12 9HQ, EnglandCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Bovey, Mark
[4
]
Cui, Yun-Hua
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机构:
Shanghai Inst Acupuncture Moxibust & Meridians, Shanghai 200030, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Cui, Yun-Hua
[5
]
Liu, Hui-Rong
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机构:
Shanghai Inst Acupuncture Moxibust & Meridians, Shanghai 200030, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Liu, Hui-Rong
[5
]
Ding, Wei
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机构:
Capital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Ding, Wei
[1
]
Wu, Huan-Gan
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机构:
Shanghai Inst Acupuncture Moxibust & Meridians, Shanghai 200030, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Wu, Huan-Gan
[5
]
Wang, Xiao-Min
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机构:
Capital Med Univ, Dept Physiol, Beijing 100069, Peoples R ChinaCapital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
Wang, Xiao-Min
[2
]
机构:
[1] Capital Med Univ, Dept Biochem & Mol Biol, Beijing 100069, Peoples R China
[2] Capital Med Univ, Dept Physiol, Beijing 100069, Peoples R China
[3] London S Bank Univ, Fac Hlth & Social Care, London SE1 0AA, England
[4] British Acupuncture Council, London W12 9HQ, England
[5] Shanghai Inst Acupuncture Moxibust & Meridians, Shanghai 200030, Peoples R China
Relevance: Acupuncture is an intrinsic part of traditional Chinese medicine. The current understanding of the acupuncture meridian system, acupoints and the potential utilizing Omics technologies are summarized in this review. Material and methods: A systematic search for acupuncture involving Omics technologies was carried out using multiple online literature databases. The records retrieved were from the full collections of each database dated to September 2011. Data produced from functional genomic technologies were extracted from the collected acupuncture/moxibustion studies and subjected to evaluation. Analyses and comments were summarized on the advances in experimental research in acupuncture/moxibustion-related studies, and the future for strategies and approaches in the era of functional genomics highlighted. Results: An overview of articles indicated that several diseases or symptoms with evidence of effectiveness had been piloted for using functional genomic technologies, such as Parkinson's disease, allergic disorders, pain, and spinal cord injury, most of which are chronic "difficult diseases". High-throughput genomic and proteomic profiling of gene expression in tissues has been able to identify potential candidates for the effects of acupuncture and provide valuable information toward understanding the possible mechanisms of the therapy. However, without further holistic and sophisticated analyses in the context of metabolomics and systems biology, the current attempts and the foreseeable developments appear to be insufficient to produce firm conclusions. Noticeably, the recent rapid advances in functional molecular imaging targeting specific metabolites have shown great promise and if combined with other post-genomic technologies, could be extremely helpful for the acupuncture studies in human subjects. Conclusion: This review suggest that disease-oriented studies using the approach of multi-indexed high-throughput technologies and systems biology analyses will be a preferred strategy for future acupuncture/moxibustion research. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Hong, Mee Sook
Park, Hun-Kuk
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Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Hun-Kuk
Yang, Jong-Soo
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Yang, Jong-Soo
Park, Hi-Joon
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Hi-Joon
Kim, Seung-Tae
论文数: 0引用数: 0
h-index: 0
机构:
Busan Natl Univ, Dept Acupuncture & Moxibust, Sch Oriental Med, Pusan 626770, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Kim, Seung-Tae
Kim, Seung-Nam
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Kim, Seung-Nam
Park, Ji-Yeun
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Ji-Yeun
Song, Jeong Yoon
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Neo Med Ctr, Seoul 134727, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Song, Jeong Yoon
Park, Hyun-Kyung
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Neo Med Ctr, Seoul 134727, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Hyun-Kyung
Jo, Dae Jean
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Neo Med Ctr, Seoul 134727, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Jo, Dae Jean
Park, Sung Wook
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kyung Hee Univ Med Ctr, Seoul 130702, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Sung Wook
HwanYun, Dong
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kyung Hee Univ Med Ctr, Seoul 130702, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
HwanYun, Dong
Ban, Ju Yeon
论文数: 0引用数: 0
h-index: 0
机构:
Dankook Univ, Coll Dent, Dept Pharmacol, Cheonan 330714, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Ban, Ju Yeon
Chung, Joo-Ho
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h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
机构:
Dongguk Univ, Med Sci Res Ctr, Gyeonggi Do, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Jeon, Songhee
Kim, Youn Jung
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h-index: 0
机构:
Kyung Hee Univ, EW Nursing Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Kim, Youn Jung
Kim, Seung-Tae
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机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Kim, Seung-Tae
Moon, Woongjoon
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Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Moon, Woongjoon
Chae, Younbyoung
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Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Chae, Younbyoung
Kang, Minjeong
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h-index: 0
机构:
Kyung Hee Univ, EW Nursing Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Kang, Minjeong
Chung, Mi-Young
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h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Chung, Mi-Young
Lee, Hyangsook
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机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Lee, Hyangsook
Hong, Mi-Sook
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Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Hong, Mi-Sook
Chung, Joo-Ho
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Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Chung, Joo-Ho
Joh, Tong H.
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h-index: 0
机构:
Cornell Univ, Weill Med Coll, Dept Neurol & Neurosci, Ithaca, NY 14853 USAKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Joh, Tong H.
Lee, Hyejung
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h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Lee, Hyejung
Park, Hi-Joon
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Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Kang, Jun Mo
Park, Hi Joon
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机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Park, Hi Joon
Choi, Yeong Gon
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机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Choi, Yeong Gon
Choe, Il Hwan
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机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Choe, Il Hwan
Park, Jae Hyun
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机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Park, Jae Hyun
Kim, Yong Sik
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h-index: 0
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Kim, Yong Sik
Lim, Sabina
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机构:
Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South KoreaKyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Hong, Mee Sook
Park, Hun-Kuk
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h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Hun-Kuk
Yang, Jong-Soo
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h-index: 0
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Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Yang, Jong-Soo
Park, Hi-Joon
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h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Hi-Joon
Kim, Seung-Tae
论文数: 0引用数: 0
h-index: 0
机构:
Busan Natl Univ, Dept Acupuncture & Moxibust, Sch Oriental Med, Pusan 626770, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Kim, Seung-Tae
Kim, Seung-Nam
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Kim, Seung-Nam
Park, Ji-Yeun
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Ji-Yeun
Song, Jeong Yoon
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Neo Med Ctr, Seoul 134727, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Song, Jeong Yoon
Park, Hyun-Kyung
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Neo Med Ctr, Seoul 134727, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Hyun-Kyung
Jo, Dae Jean
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Neo Med Ctr, Seoul 134727, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Jo, Dae Jean
Park, Sung Wook
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kyung Hee Univ Med Ctr, Seoul 130702, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Park, Sung Wook
HwanYun, Dong
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kyung Hee Univ Med Ctr, Seoul 130702, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
HwanYun, Dong
Ban, Ju Yeon
论文数: 0引用数: 0
h-index: 0
机构:
Dankook Univ, Coll Dent, Dept Pharmacol, Cheonan 330714, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
Ban, Ju Yeon
Chung, Joo-Ho
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South Korea
机构:
Dongguk Univ, Med Sci Res Ctr, Gyeonggi Do, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Jeon, Songhee
Kim, Youn Jung
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Nursing Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Kim, Youn Jung
Kim, Seung-Tae
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Kim, Seung-Tae
Moon, Woongjoon
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Moon, Woongjoon
Chae, Younbyoung
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Chae, Younbyoung
Kang, Minjeong
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, EW Nursing Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Kang, Minjeong
Chung, Mi-Young
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Chung, Mi-Young
Lee, Hyangsook
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Lee, Hyangsook
Hong, Mi-Sook
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Hong, Mi-Sook
Chung, Joo-Ho
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Kohwang Med Res Inst, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Chung, Joo-Ho
Joh, Tong H.
论文数: 0引用数: 0
h-index: 0
机构:
Cornell Univ, Weill Med Coll, Dept Neurol & Neurosci, Ithaca, NY 14853 USAKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Joh, Tong H.
Lee, Hyejung
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
Lee, Hyejung
Park, Hi-Joon
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South KoreaKyung Hee Univ, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Kang, Jun Mo
Park, Hi Joon
论文数: 0引用数: 0
h-index: 0
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Park, Hi Joon
Choi, Yeong Gon
论文数: 0引用数: 0
h-index: 0
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Choi, Yeong Gon
Choe, Il Hwan
论文数: 0引用数: 0
h-index: 0
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Choe, Il Hwan
Park, Jae Hyun
论文数: 0引用数: 0
h-index: 0
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Park, Jae Hyun
Kim, Yong Sik
论文数: 0引用数: 0
h-index: 0
机构:Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea
Kim, Yong Sik
Lim, Sabina
论文数: 0引用数: 0
h-index: 0
机构:
Kyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South KoreaKyung Hee Univ, Coll Korean Med, Dept Meridian & Acupoints, Seoul, South Korea