Palladium catalyzed dehydrogenative arylation of coumarins: an unexpected switch in regioselectivity

被引：50
作者：
Jafarpour, Farnaz [1 ]
Hazrati, Hamideh [1 ]
Mohasselyazdi, Nazanin [1 ]
Khoobi, Mehdi [2 ,3 ]
Shafiee, Abbas [2 ,3 ]
机构：
[1] Univ Tehran, Sch Chem, Coll Sci, Tehran, Iran
[2] Univ Tehran Med Sci, Dept Med Chem, Fac Pharm, Tehran 14176, Iran
[3] Univ Tehran Med Sci, Pharmaceut Sci Res Ctr, Tehran 14176, Iran
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 93期
基金：
美国国家科学基金会;
关键词：
C-H FUNCTIONALIZATION; CROSS-COUPLING REACTIONS; BOND ACTIVATION; SIMPLE ARENES; DERIVATIVES; HETEROARENES; INHIBITORS; AGENTS; 3-PHENYLCOUMARINS; INDOLES/PYRROLES;
D O I：
10.1039/c3cc46959j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new regioselective alpha-arylation of coumarins with unactivated simple arenes via a palladium-catalyzed twofold C-H functionalization is devised. This method offers an attractive new approach to synthesis of a wide variety of 3-arylcoumarins from readily accessible starting materials.
引用
收藏
页码：10935 / 10937
页数：3
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