Titanium(IV)(salen) and vanadium(V)(salen) complexes derived from C2- and C1-symmetric diamines for asymmetric cyanohydrin synthesis

被引：11

作者：

Belokon, Yuri N. ^{[3
]}

Hunt, Jamie ^{[1
,2
]}

North, Michael ^{[1
,2
]}

机构：

[1] Newcastle Univ, Sch Chem, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[2] Newcastle Univ, Univ Res Ctr Catalysis & Intensified Proc, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[3] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Moscow 119991, Russia

来源：

SYNLETT | 2008年 / 14期

关键词：

cyanohydrins; homogenous catalysis; asymmetric catalysis; Schiff bases; titanium;

D O I：

10.1055/s-2008-1077900

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Titanium and vanadium salen complexes have been prepared from C-2- and C-1-symmetric acyclic diamines. All of the complexes catalysed the asymmetric addition of trimethylsilyl cyanide to benzaldehyde and the sense of asymmetric induction was determined by the nature of the substituents. The vanadium complex of a valine-derived diamine gave good results with a range of aromatic and aliphatic aldehydes.

引用

页码：2150 / 2154

页数：5

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