Rapid entry to enantiopure carbacepham derivatives via Lewis acid promoted carbonyl-ene cyclization of 2-azetidinone-tethered alkenylaldehydes

被引：15

作者：

Alcaide, B ^{[1
]}

Pardo, C ^{[1
]}

Rodríguez-Ranera, C ^{[1
]}

Rodríguez-Vicente, A ^{[1
]}

机构：

[1] Univ Complutense Madrid, Fac Ciencias Quim, Dept Quim Organ 1, E-28040 Madrid, Spain

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 26期

关键词：

D O I：

10.1021/ol016871a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Lewis acid promoted types I and II carbonyl-ene cyclizations of 2-azetidinone-tethered alkenylaldehydes are used for the rapid, highly diastereoselective synthesis of polyfunctionalized, enantiomerically pure carbacepham derivatives.

引用

页码：4205 / 4208

页数：4

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