Latent drop-out based transitions in linear quantile hidden Markov models for longitudinal responses with attrition

被引:10
作者
Marino, Maria Francesca [1 ]
Alfo, Marco [2 ]
机构
[1] Univ Perugia, I-06100 Perugia, Italy
[2] Univ Roma La Sapienza, I-00185 Rome, Italy
关键词
Quantile regression; Longitudinal data; Hidden Markov models; Latent drop-out classes; PATTERN-MIXTURE-MODELS; REGRESSION-MODELS; INCOMPLETE DATA;
D O I
10.1007/s11634-015-0222-x
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Longitudinal data are characterized by the dependence between observations from the same individual. In a regression perspective, such a dependence can be usefully ascribed to unobserved features (covariates) specific to each individual. On these grounds, random parameter models with time-constant or time-varying structure are now well established in the generalized linear model context. In the quantile regression framework, specifications based on random parameters have only recently known a flowering interest. We start from the recent proposal by Farcomeni (Stat Comput 22:141-152, 2012) on longitudinal quantile hidden Markov models, and extend it to handle potentially informative missing data mechanisms. In particular, we focus on monotone missingness which may lead to selection bias and, therefore, to unreliable inferences on model parameters. We detail the proposed approach by re-analyzing a well known dataset on the dynamics of CD4 cell counts in HIV seroconverters and by means of a simulation study reported in the supplementary material.
引用
收藏
页码:483 / 502
页数:20
相关论文
共 31 条
[2]  
[Anonymous], 2010, Agresti
[3]  
Bartolucci F., 2013, Latent Markov Models for Longitudinal Data
[4]   A Discrete Time Event-History Approach to Informative Drop-Out in Mixed Latent Markov Models with Covariates [J].
Bartolucci, Francesco ;
Farcomeni, Alessio .
BIOMETRICS, 2015, 71 (01) :80-89
[5]   A MAXIMIZATION TECHNIQUE OCCURRING IN STATISTICAL ANALYSIS OF PROBABILISTIC FUNCTIONS OF MARKOV CHAINS [J].
BAUM, LE ;
PETRIE, T ;
SOULES, G ;
WEISS, N .
ANNALS OF MATHEMATICAL STATISTICS, 1970, 41 (01) :164-&
[6]   ESTIMATING THE ASYMPTOTIC COVARIANCE-MATRIX FOR QUANTILE REGRESSION-MODELS - A MONTE-CARLO STUDY [J].
BUCHINSKY, M .
JOURNAL OF ECONOMETRICS, 1995, 68 (02) :303-338
[7]   MAXIMUM LIKELIHOOD FROM INCOMPLETE DATA VIA EM ALGORITHM [J].
DEMPSTER, AP ;
LAIRD, NM ;
RUBIN, DB .
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-METHODOLOGICAL, 1977, 39 (01) :1-38
[8]   Longitudinal quantile regression in the presence of informative dropout through longitudinal-survival joint modeling [J].
Farcomeni, Alessio ;
Viviani, Sara .
STATISTICS IN MEDICINE, 2015, 34 (07) :1199-1213
[9]   Quantile regression for longitudinal data based on latent Markov subject-specific parameters [J].
Farcomeni, Alessio .
STATISTICS AND COMPUTING, 2012, 22 (01) :141-152
[10]   Quantile regression for longitudinal data using the asymmetric Laplace distribution [J].
Geraci, Marco ;
Bottai, Matteo .
BIOSTATISTICS, 2007, 8 (01) :140-154