Improving understanding of research consent in middle-aged and elderly patients with psychotic disorders

被引:96
作者
Dunn, LB [1 ]
Lindamer, LA [1 ]
Palmer, BW [1 ]
Golshan, S [1 ]
Schneiderman, LJ [1 ]
Jeste, DV [1 ]
机构
[1] Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA
关键词
D O I
10.1176/appi.ajgp.10.2.142
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Individuals with schizophrenia may show impaired capacity to make decisions about participating in research, yet these patients also show considerable heterogeneity in decisional abilities. Problems with procedures contribute to patients' difficulties in understanding consent forms. Few studies have focused on improving comprehension of research consent in older patients with psychotic disorders. In this study; 80 middle-aged and elderly outpatients with schizophrenia or related psychotic disorders and 19 normal comparison subjects were randomized to receive a routine consent (RC) or enhanced consent (EC) procedure. The EC procedure consisted of a computerized slide show incorporating more structure and review of important information, A comprehension test was administered after the consent procedure; subjects were given up to three trials of the post-test to answer all of the questions correctly. Overall, the normal comparison subjects obtained a higher score on the post-consent comprehension test than the patients. Within each of these two groups, those who received EC bad better comprehension than those who received RC Interestingly; EC patients did not differ significantly from RC normal comparison subjects in their post-test scores. Among the patients, comprehension test scores correlated with level of education and cognitive performance.
引用
收藏
页码:142 / 150
页数:9
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