Full-wave modeling of micro-acoustofluidic devices driven by standing surface acoustic waves for microparticle acoustophoresis

被引:39
作者
Hsu, Jin-Chen [1 ]
Chao, Chih-Lei [1 ]
机构
[1] Natl Yunlin Univ Sci & Technol, Dept Mech Engn, Touliu 64002, Yunlin, Taiwan
关键词
RADIATION FORCES; SINGLE CELLS; MANIPULATION; SEPARATION; CHIP; PROPAGATION; PARTICLES; SAW;
D O I
10.1063/5.0017933
中图分类号
O59 [应用物理学];
学科分类号
摘要
Surface acoustic wave (SAW)-based acoustofluidic systems are emerging as an important tool for acoustophoresis. In this paper, we present a full cross-sectional model of standing SAW acoustofluidic devices for obtaining full-wave results. Our model involves a piezoelectric substrate with interdigitated electrodes and a rectangular water channel enclosed in a finite soft elastic solid. This model accounts for piezoelectric SAWs with electromechanical coupling, simultaneous transverse and longitudinal wave fields in the elastic solid from SAW radiation, and acoustic and streaming fields in the enclosed water channel in an integrated system by solving the elastodynamic and Navier-Stokes field equations. Accordingly, the acoustic radiation force and streaming-induced Stokes drag force are obtained to analyze the acoustophoretic motion of microparticles of different sizes. Using the full-wave results, we reveal the influences of the channel wall displacements and acoustic and flow fields in the water domain. The full-wave field also allows us to determine the effects of the channel dimensions and its location in the finite elastic solid on the force strengths. We demonstrate that the critical diameter of the microparticles can be reduced by an order of magnitude by changing the channel location, while maintaining the same acoustic frequency. We note that the results, mechanisms, and method presented in this study can be usefully applied to the rational design of standing SAW acoustofluidic devices and for developing innovative acoustophoretic systems involving complex structure-fluid interactions. Published under license by AIP Publishing.
引用
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页数:15
相关论文
共 67 条
[21]   The importance of travelling wave components in standing surface acoustic wave (SSAW) systems [J].
Devendran, Citsabehsan ;
Albrecht, Thomas ;
Brenker, Jason ;
Alan, Tuncay ;
Neild, Adrian .
LAB ON A CHIP, 2016, 16 (19) :3756-3766
[22]   Cell separation using tilted-angle standing surface acoustic waves [J].
Ding, Xiaoyun ;
Peng, Zhangli ;
Lin, Sz-Chin Steven ;
Geri, Michela ;
Li, Sixing ;
Li, Peng ;
Chen, Yuchao ;
Dao, Ming ;
Suresh, Subra ;
Huang, Tony Jun .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (36) :12992-12997
[23]   On-chip manipulation of single microparticles, cells, and organisms using surface acoustic waves [J].
Ding, Xiaoyun ;
Lin, Sz-Chin Steven ;
Kiraly, Brian ;
Yue, Hongjun ;
Li, Sixing ;
Chiang, I-Kao ;
Shi, Jinjie ;
Benkovic, Stephen J. ;
Huang, Tony Jun .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (28) :11105-11109
[24]   Acoustic streaming generated by two orthogonal standing waves propagating between two rigid walls [J].
Doinikov, Alexander A. ;
Thibault, Pierre ;
Marmottant, Philippe .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 2017, 141 (02) :1282-1289
[25]   Microscale acoustofluidics: Microfluidics driven via acoustics and ultrasonics [J].
Friend, James ;
Yeo, Leslie Y. .
REVIEWS OF MODERN PHYSICS, 2011, 83 (02) :647-704
[26]   Three-dimensional manipulation of single cells using surface acoustic waves [J].
Guo, Feng ;
Mao, Zhangming ;
Chen, Yuchao ;
Xie, Zhiwei ;
Lata, James P. ;
Li, Peng ;
Ren, Liqiang ;
Liu, Jiayang ;
Yang, Jian ;
Dao, Ming ;
Suresh, Subra ;
Huang, Tony Jun .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (06) :1522-1527
[27]   Radiation dominated acoustophoresis driven by surface acoustic waves [J].
Guo, Jinhong ;
Kang, Yuejun ;
Ai, Ye .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2015, 455 :203-211
[28]   RF-Activated Standing Surface Acoustic Wave for On-Chip Particle Manipulation [J].
Guo, Jinhong ;
Li, Joshua L. W. ;
Chen, Yu ;
Yeo, Leslie Y. ;
Friend, James R. ;
Kang, Yuejun .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 2014, 62 (09) :1898-1904
[29]   Trapping and patterning of large particles and cells in a 1D ultrasonic standing wave [J].
Habibi, Ruhollah ;
Devendran, Citsabehsan ;
Neild, Adrian .
LAB ON A CHIP, 2017, 17 (19) :3279-3290
[30]   Numerical simulation of acoustofluidic manipulation by radiation forces and acoustic streaming for complex particles [J].
Hahn, Philipp ;
Leibacher, Ivo ;
Baasch, Thierry ;
Dual, Jurg .
LAB ON A CHIP, 2015, 15 (22) :4302-4313