Balancing Risk and Reward in Target Delineation for Highly Conformal Radiotherapy in Head and Neck Cancer

被引:52
作者
Eisbruch, Avraham [1 ]
Gregoire, Vincent [2 ,3 ]
机构
[1] Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA
[2] Catholic Univ Louvain, Dept Radiat Oncol, St Luc Univ Hosp, B-1200 Brussels, Belgium
[3] Catholic Univ Louvain, St Luc Univ Hosp, Ctr Mol Imaging & Expt Radiotherapy, B-1200 Brussels, Belgium
关键词
INTENSITY-MODULATED RADIOTHERAPY; POSITRON-EMISSION-TOMOGRAPHY; SQUAMOUS-CELL CARCINOMA; LOCALLY ADVANCED HEAD; FDG-PET; RADIATION-THERAPY; NASOPHARYNGEAL CARCINOMA; VOLUME DELINEATION; DOSE DISTRIBUTION; PAROTID-GLAND;
D O I
10.1016/j.semradonc.2008.09.008
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The therapeutic index of highly conformal radiotherapy (RT) depends on adequate selection and delineation of the gross tumor volumes, the clinical target volumes, and the tissues and organs whose sparing is likely to gain clinical benefit. Decisions about target and tissue selection and delineation affect the balance of reward and the risk of highly conformal RT. Some of these issues relating to head and neck cancer, including target delineation after tumor shrinkage by induction chemotherapy or at midradiotherapy, are discussed in this article. © 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:43 / 52
页数:10
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