C/EBPα mutations in acute myeloid leukaemias

被引:217
作者
Nerlov, C [1 ]
机构
[1] European Mol Biol Lab, Mouse Biol Programme, I-00016 Monterotondo, Italy
关键词
D O I
10.1038/nrc1363
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Specific mutations in the gene that encodes the multifunctional transcription factor C/EBPalpha are frequently associated with acute myeloid leukaemias. Are only a specific subset of the functions of C/EBPalpha therefore involved in leukaemogenesis?
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收藏
页码:394 / 400
页数:7
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