Synthesis and Antimicrobial Activities of Some New Heterocyclic Compounds Based on 6-Chloropyridazine-3(2H)-thione

被引：23

作者：

Abd El-Salam, Nasser M. ^{[1
]}

Mostafa, Mohamed S. ^{[2
]}

Ahmed, Gamal A. ^{[3
]}

Alothman, Othman Y. ^{[4
]}

机构：

[1] King Saud Univ, Riyadh Community Coll, Riyadh 11437, Saudi Arabia

[2] Jazan Univ, Fac Sci, Dept Chem, Jazan, Saudi Arabia

[3] Zagazig Univ, Fac Sci, Dept Chem, Zagazig 44519, Egypt

[4] King Saud Univ, Coll Engn, Dept Chem Engn, Riyadh 11421, Saudi Arabia

来源：

JOURNAL OF CHEMISTRY | 2013年 / 2013卷

关键词：

PYRIDAZINE DERIVATIVES SYNTHESIS; CHEMISTRY;

D O I：

10.1155/2013/890617

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three tricyclic ring system, pyridazino[6,1-b]quinazolin-10-ones, benzimidazolo-pyridazine thione, and 1,2,4-benzotriazino-pyridazinethione along with imidazo-[1,2-b]-pyridazinethione, 1,2,4-triazolo[4,3-b]pyridazine-thione derivatives were synthesized starting from6-chloropyridazin3-(2H)-thione. Some disulfide and sulfide derivatives were also prepared. The antimicrobial activity of the synthesized compounds was tested. Some of these compounds possess a highly response against gram-positive and gram-negative bacteria as well as fungi.

引用

页数：8

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