Pancreatic atrophy and diabetes mellitus following blunt abdominal trauma

被引:6
作者
Edwards, Mary J. [1 ]
Crudo, David F. [2 ]
Carlson, Terri L. [1 ]
Pedersen, Anita M. [3 ]
Keller, Laura [3 ]
机构
[1] TAMC, Dept Surg, Honolulu, HI 96859 USA
[2] Wake Forest Univ, Dept Pediat, Winston Salem, NC 27109 USA
[3] TAMC, Dept Pediat, Honolulu, HI 96859 USA
关键词
Pediatric; Pancreatic injury; Pancreatic atrophy; Type 1 diabetes mellitus; Blunt abdominal trauma; NONOPERATIVE MANAGEMENT; DISTAL PANCREATECTOMY; DUCT SYNDROME; CHILDREN; TRANSECTION; GENETICS; OUTCOMES; INJURY; HUMANS;
D O I
10.1016/j.jpedsurg.2012.11.030
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Following pancreatic trauma, loss of uninjured parenchyma as a result of surgical management is expected, and atrophy of parenchyma following nonoperative management has been described. While endocrine insufficiency as a sequela of pancreatic trauma has been reported in adults, it is not a described entity in children. We report a case of pancreatic atrophy following blunt injury in an 8 year old boy who presented 3 years later with diabetes mellitus. Further analysis revealed significant genetic predisposition to diabetes. Published by Elsevier Inc.
引用
收藏
页码:432 / 435
页数:4
相关论文
共 21 条
[1]  
Al-Ahmadi K, 2008, CAN J SURG, V51, P118
[2]   Clinical Applications of Diabetes Antibody Testing [J].
Bingley, Polly J. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (01) :25-33
[3]  
Borkon MJ, 2011, AM SURGEON, V77, P612
[4]   Pancreatic injury in children: good outcome of nonoperative treatment [J].
de Blaauw, Ivo ;
Winkelhorst, J. Tomas ;
Rieu, Paul N. ;
van der Staak, Frans H. ;
Wijnen, Marc H. ;
Severijnen, Rene S. V. M. ;
van Vugt, Arie B. ;
Wijnen, Rene M. H. .
JOURNAL OF PEDIATRIC SURGERY, 2008, 43 (09) :1640-1643
[5]   Better preservation of endocrine function after central versus distal pancreatectomy for mid-gland lesions [J].
DiNorcia, Joseph ;
Ahmed, League ;
Lee, Minna K. ;
Reavey, Patrick L. ;
Yakaitis, Elizabeth A. ;
Lee, James A. ;
Schrope, Beth A. ;
Chabot, John A. ;
Allendorf, John D. .
SURGERY, 2010, 148 (06) :1247-1254
[6]   HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the Type 1 Diabetes Genetics Consortium families [J].
Erlich, Henry ;
Valdes, Ana Maria ;
Noble, Janelle ;
Carlson, Joyce A. ;
Varney, Mike ;
Concannon, Pat ;
Mychaleckyj, Josyf C. ;
Todd, John A. ;
Bonella, Persia ;
Fear, Anna Lisa ;
Lavant, Eva ;
Louey, Anthony ;
Moonsamy, Priscilla .
DIABETES, 2008, 57 (04) :1084-1092
[7]   Roux-en-Y internal drainage is the best surgical option to treat patients with disconnected duct syndrome after severe acute pancreatitis [J].
Howard, TJ ;
Rhodes, GJ ;
Selzer, DJ ;
Sherman, S ;
Fogel, E ;
Lehman, GA .
SURGERY, 2001, 130 (04) :714-719
[8]   Long-term results of distal pancreatectomy for chronic pancreatitis in 90 patients [J].
Hutchins, RR ;
Hart, RS ;
Pacifico, M ;
Bradley, NJ ;
Williamson, RCN .
ANNALS OF SURGERY, 2002, 236 (05) :612-618
[9]  
Kertai Michael A, 2010, J Trauma, V68, pE44, DOI 10.1097/TA.0b013e31815edecd
[10]   Early operation in children with pancreas transection [J].
Meier, DE ;
Coln, CD ;
Hicks, BA ;
Guzzetta, PC .
JOURNAL OF PEDIATRIC SURGERY, 2001, 36 (02) :341-343