Technical aspects of amyloid imaging for Alzheimer's disease

被引：8
作者：
Edison, Paul [1 ,3 ]
Hinz, Rainer [2 ]
Brooks, David J. [1 ,3 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, MRC, Ctr Clin Sci, London W12 0NN, England
[2] Univ Manchester, Wolfson Mol Imaging Ctr, Manchester M20 3LJ, Lancs, England
[3] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Div Neurosci, London W12 0NN, England
来源：
ALZHEIMERS RESEARCH & THERAPY | 2011年 / 3卷 / 04期
基金：
英国医学研究理事会;
关键词：
POSITRON-EMISSION-TOMOGRAPHY; BRAIN TRANSFER CONSTANTS; PITTSBURGH COMPOUND-B; TIME UPTAKE DATA; GRAPHICAL EVALUATION; PET; BETA; DEMENTIA; BINDING; F-18;
D O I：
10.1186/alzrt87
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
[C-11] Pittsburgh Compound B positron emission tomography has now been extensively used to evaluate the amyloid load in different types of dementia and has become a powerful research tool in the field of neurodegenerative diseases. In the present short review we discuss the properties of amyloid imaging agent [C-11] Pittsburgh Compound B, the different modalities of molecular imaging, image processing and data analysis, and newer amyloid imaging agents.
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页数：8
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