Trends in Bronchiectasis Among Medicare Beneficiaries in the United States, 2000 to 2007

被引:225
|
作者
Seitz, Amy E. [1 ,2 ]
Olivier, Kenneth N. [1 ,2 ]
Adjemian, Jennifer [1 ,2 ]
Holland, Steven M. [2 ]
Prevots, D. Rebecca [1 ,2 ]
机构
[1] NIAID, NIH, Epidemiol Unit, Bethesda, MD 20892 USA
[2] NIAID, NIH, Lab Clin Infect Dis, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
BEAM COMPUTED-TOMOGRAPHY; IDIOPATHIC BRONCHIECTASIS; ORPHAN DISEASE; ACCURACY;
D O I
10.1378/chest.11-2209
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Bronchiectasis is a potentially serious condition characterized by permanent and abnormal widening of the airways, the prevalence of which is not well described. We sought to describe the trends, associated conditions, and risk factors for bronchiectasis among adults aged >= 65 years. Methods: A 5% sample of the Medicare outpatient claims database was analyzed for bronchicctasis trends among beneficiaries aged >= 65 years from 2000 to 2007. Bronchiectasis was identified using International Classification of Diseases, Ninth Revision, Clinical Modification claim diagnosis codes for acquired bronchiectasis. Period prevalence was used to describe sex- and race/ethnicity-specific rates, and annual prevalence was used to describe trends and age-specific rates. We estimated trends using Poisson regression and odds of bronchiectasis using multivariate logistic regression. Results: From 2000 to 2007, 22,296 people had at least one claim for bronchiectasis. The 8-year period prevalence of bronchiectasis was 1,106 cases per 100,000 people. Bronchiectasis increased by 8.7% per year. We identified an interaction between the number of thoracic CT scans and race/ethnicity; period prevalence varied by a greater degree by number of thoracic CT scans among Asians compared with whites or blacks. Among people with one CT scan, Asians had a 2.5- and 3.9-fold higher period prevalence compared with whites and blacks. Conclusions: Bronchiectasis prevalence increased significantly from 2000 to 2007 in the Medicare outpatient setting and varied by age, sex, and race/ethnicity. This increase could be due to a true increase in the condition or an increased recognition of previously undiagnosed cases. CHEST 2012; 142(2):432-439
引用
收藏
页码:432 / 439
页数:8
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