Impact of lifestyle and environmental factors on male reproductive health

被引：2
作者：
Schuppe, Hans-Christian [1 ]
Koehn, Frank-Michael [2 ]
机构：
[1] Justus Liebig Univ Giessen, Univ Klinikum Giessen & Marburg GmbH Standort Gie, Klin & Poliklin Urol Kinderurol & Androl, Sekt Konservat Androl, Gaffkystr 14, D-35385 Giessen, Germany
[2] Androl Munchen, Munich, Germany
来源：
UROLOGIE | 2022年 / 61卷 / 11期
关键词：
Spermatogenesis; Toxicants; Sperm; Semen; Drugs; IN-VITRO FERTILIZATION; SEMEN QUALITY; PHYSICAL-ACTIVITY; TESTICULAR FUNCTION; SPERM PARAMETERS; ALCOHOL INTAKE; FERTILITY; ASSOCIATION; INFERTILITY; EXPOSURE;
D O I：
10.1007/s00120-022-01951-z
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The identification of potential environmental hazards is of clinical relevance for the diagnosis of male infertility. Knowledge about these factors will improve prevention of fertility disorders. Apart from drugs or factors related to lifestyle such as alcohol and tobacco smoke, various environmental and occupational agents, both chemical and physical, may impair male reproduction. Reproductive toxicity may evolve at the hypothalamic-pituitary, testicular, or posttesticular level; endpoints comprise deterioration of spermatogenesis and sperm function as well as endocrine disorders and sexual dysfunction. However, due to the complex regulation of the male reproductive system, information regarding single exogenous factors and their mechanisms of action in humans is limited. This is also due to the fact that extrapolation of results obtained from experimental animal or in vitro studies remains difficult. Nevertheless, the assessment of relevant exposures to reproductive toxicants should be carefully evaluated during diagnostic procedures of andrological patients.
引用
收藏
页码：1217 / 1228
页数：12
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