Unsaturated guluronate oligosaccharide used as a stabilizer of oil-in-water nanoemulsions loaded with bioactive nutrients

被引:5
作者
Bi, Decheng [1 ,2 ]
Li, Meiting [1 ,3 ]
Zhu, Nanting [1 ]
Yao, Lijun [1 ]
Fang, Weishan [4 ]
Wu, Yan [5 ]
Xu, Hong [1 ]
Hu, Zhangli [1 ]
Xu, Xu [1 ]
机构
[1] Shenzhen Univ, Coll Life Sci & Oceanog, Shenzhen Key Lab Marine Bioresources & Ecol, Shenzhen 518060, Peoples R China
[2] Shenzhen Univ, Coll Phys & Optoelect Engn, Shenzhen 518060, Peoples R China
[3] Shenzhen Technol Univ, Qual & Stand Acad, Shenzhen 518118, Peoples R China
[4] Shenzhen Univ, Sch Basic Med Sci, Dept Expt Teaching Ctr, Shenzhen 518060, Peoples R China
[5] Shenzhen Univ, Instrumental Anal Ctr, Shenzhen 518060, Peoples R China
基金
国家重点研发计划; 中国国家自然科学基金;
关键词
Unsaturated guluronate oligosaccharide; O; W nanoemulsion; Resveratrol; Sustained release; Antioxidant activity; RESVERATROL; CURCUMIN;
D O I
10.1016/j.fochx.2022.100469
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Unsaturated guluronate oligosaccharide (GOS) is generated via alginate-derived polyguluronate (PG) degrada-tion by alginate lyase, followed by formation of a double bond between C-4 and C-5 at the nonreducing end. In this study, GOS was first used as a stabilizer to fabricate O/W nanoemulsions loaded with resveratrol (GOS-RES). Our results revealed that both the GOS-RES and normal O/W resveratrol nanoemulsions (water-RES) showed small droplet sizes and narrow size distributions under certain experimental conditions. However, the particle size and stability of the GOS-RES were slightly greater than those of the water-RES in acidic and neutral envi-ronments and at high temperatures. Furthermore, the GOS-RES exhibited a better sustained release effect for resveratrol than the water-RES. Moreover, the GOS-RES showed a significant superoxide radical scavenging effect. All these results demonstrated that GOS has good prospects for preparing nanoemulsions to encapsulate hydrophobic nutrients, which could be applied as food-grade components in beverages and other foods.
引用
收藏
页数:6
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