Improvement of auditory hallucinations and reduction of primary auditory area's activation following TMS

被引：16

作者：

Giesel, Frederik L. ^{[2
,3
]}

Mehndiratta, Amit ^{[1
,2
]}

Hempel, Albrecht ^{[4
]}

Hempel, Eckhard ^{[5
]}

Kress, Kai R. ^{[4
]}

Essig, Marco ^{[2
]}

Schroeder, Johannes ^{[4
]}

机构：

[1] Univ Oxford Keble Coll, Oxford OX1 3PG, England

[2] German Canc Res Ctr, D-6900 Heidelberg, Germany

[3] Univ Heidelberg, Dept Nucl Med, D-6900 Heidelberg, Germany

[4] Univ Heidelberg, Dept Psychiat, Sect Geriatr Psychiat, D-6900 Heidelberg, Germany

[5] Siemens Med Solut, Eschborn, Germany

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2012年 / 81卷 / 06期

关键词：

Auditory hallucinations; Transcranial magnetic stimulation; Schizophrenia; TRANSCRANIAL MAGNETIC STIMULATION; VERBAL HALLUCINATIONS; SCHIZOPHRENIA; SPEECH; CORTEX;

D O I：

10.1016/j.ejrad.2011.03.002

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Background: In the present case study, improvement of auditory hallucinations following transcranial magnetic stimulation (TMS) therapy was investigated with respect to activation changes of the auditory cortices. Methods: Using functional magnetic resonance imaging (fMRI), activation of the auditory cortices was assessed prior to and after a 4-week TMS series of the left superior temporal gyrus in a schizophrenic patient with medication-resistant auditory hallucinations. Results: Hallucinations decreased slightly after the third and profoundly after the fourth week of TMS. Activation in the primary auditory area decreased, whereas activation in the operculum and insula remained stable. Conclusions: Combination of TMS and repetitive fMRI is promising to elucidate the physiological changes induced by TMS. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：1273 / 1275

页数：3

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