Biological Activities and Chemical Composition of Santolina africana Jord. et Fourr. Aerial Part Essential Oil from Algeria: Occurrence of Polyacetylene Derivatives

被引:8
作者
Malti, Charaf Eddine Watheq [1 ]
Baccati, Clementine [2 ]
Mariani, Magali [2 ]
Hassani, Faical [3 ]
Babali, Brahim [3 ]
Atik-Bekkara, Fewzia [1 ]
Paoli, Mathieu [2 ]
Maury, Jacques [2 ]
Tomi, Felix [2 ]
Bekhechi, Chahrazed [1 ]
机构
[1] Univ Abou Bekr Belkaid Tlemcen, Dept Biol, Lab Prod Nat, Imama Tlemcen 13000, Algeria
[2] Univ Corse, CNRS, UMR 6134, SPE, Route Sanguinaires, F-20000 Ajaccio, France
[3] Univ Abou Bekr Belkaid Tlemcen, Dept Ecol & Environm, Lab Ecol & Gest Ecosyst Nat, Imama Tlemcen 13000, Algeria
关键词
Santolina africana Jord; et Fourr; Asteraceae; essential oil composition; C-13-NMR; antimicrobial activity; antioxidant activity; anti-inflammatory activity; ANTIMICROBIAL ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITIES; CHAMAECYPARISSUS L; ROSMARINIFOLIA L; CONSTITUENTS; ANTIOXIDANT; ANGUSTIFOLIA; INHIBITION; EXTRACTION;
D O I
10.3390/molecules24010204
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The chemical composition of 18 oil samples of Santolina africana isolated from aerial parts at full flowering, collected in three locations in eastern Algeria was determined by GC(RI), GC/MS and C-13-NMR analysis. The major components were: germacrene D, myrcene, spathulenol, -bisabolol, -pinene, 1,8-cineole, cis-chrysanthenol, capillene, santolina alcohol, camphor, terpinen-4-ol and lyratol. The chemical composition appeared homogeneous and characterized by the occurrence of four derivatives which exhibited a conjugated alkene dialkyne moiety. They were identified for the first time in an essential oil from S. africana. The collective oil sample exhibited moderate antimicrobial and antioxidant activities whereas the anti-inflammatory activity presented a real potential. IC50 value of Santolina africana essential oil (0.065 +/- 0.004 mg/mL) is 5-fold higher than IC50 value of NDGA used as positive control.
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页数:15
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共 61 条
[1]   Antifungal activities of Origanum vulgare subsp. hirtum, Mentha spicata, Lavandula angustifolia, and Salvia fruticosa essential oils against human pathogenic fungi [J].
Adam, K ;
Sivropoulou, A ;
Kokkini, S ;
Lanaras, T ;
Arsenakis, M .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (05) :1739-1745
[2]  
Ahmed Nouasri, 2015, Journal of Coastal Life Medicine, V3, P220, DOI 10.12980/JCLM.3.201514J83
[3]   Acaricidal activities of Santolina africana and Hertia cheirifolia essential oils against the two-spotted spider mite (Tetranychus urticae) [J].
Attia, Sabrine ;
Grissa, Kaouthar L. ;
Mailleux, Anne C. ;
Heuskin, Stephanie ;
Lognay, Georges ;
Hance, Thierry .
PEST MANAGEMENT SCIENCE, 2012, 68 (07) :1069-1076
[4]   Essential oil composition of the flowerheacls of Chtysanthemum coronarium L. from Greece [J].
Basta, Andriani ;
Pavlovic, Milica ;
Couladis, Maria ;
Tzakou, Olga .
FLAVOUR AND FRAGRANCE JOURNAL, 2007, 22 (03) :197-200
[5]   Chemical Composition, Antioxidant, Anti-Inflammatory and Anti-Proliferative Activities of Essential Oils of Plants from Burkina Faso [J].
Bayala, Bagora ;
Bassole, Imael Henri Nestor ;
Gnoula, Charlemagne ;
Nebie, Roger ;
Yonli, Albert ;
Morel, Laurent ;
Figueredo, Gilles ;
Nikiema, Jean-Baptiste ;
Lobaccaro, Jean-Marc A. ;
Simpore, Jacques .
PLOS ONE, 2014, 9 (03)
[6]   Chemical composition and bioactivities of the polyphenolic-rich extract of Ormenis africana Jord. and Fourr [J].
Bejaoui, Afef ;
Boulila, Abdennacer ;
Ben Salem, Issam ;
Boussaid, Mohamed .
INTERNATIONAL JOURNAL OF FOOD PROPERTIES, 2017, 20 (08) :1786-1795
[7]   Antioxidant activity of ethanolic extract of inflorescence of Ormenis Africana in vitro and in cell cultures [J].
Ben Mansour, Riadh ;
Gargouri, Bochra ;
Bouaziz, Mohamed ;
Elloumi, Nesrine ;
Jilani, Imtinene Belhadj ;
Ghrabi, Zaineb ;
Lassoued, Saloua .
LIPIDS IN HEALTH AND DISEASE, 2011, 10
[8]  
Bighelli A., 2009, ESSENTIAL OIL BEARIN, P195
[9]   ANTIOXIDANT DETERMINATIONS BY THE USE OF A STABLE FREE RADICAL [J].
BLOIS, MS .
NATURE, 1958, 181 (4617) :1199-1200
[10]   POLYACETYLENVERBINDUNGEN .56. NEUE ACETYLENVERBINDUNGEN AUS CHRYSANTHEMUM-ARTEN [J].
BOHLMANN, F ;
BORNOWSKI, H ;
KLEINE, KM ;
HERBST, P ;
ARNDT, C .
CHEMISCHE BERICHTE-RECUEIL, 1964, 97 (04) :1179-&