In vitro antioxidant activities of the polysaccharides from Pleurotus tuber-regium (Fr.) Sing.

被引:61
作者
Wu, Guang-Hong [1 ]
Hu, Ting [2 ]
Li, Zi-Yi [1 ]
Huang, Zhuo-Lie [1 ]
Jiang, Jian-Guo [2 ]
机构
[1] South China Agr Univ, Coll Life Sci, Guangdong Prov Key Lab Prot Funct & Regulat Agr O, Guangzhou 510642, Guangdong, Peoples R China
[2] South China Agr Univ, Coll Food & Bioengn, Guangzhou 510640, Guangdong, Peoples R China
关键词
Pleurotus tuber-regium (Fr.) Sing; Polysaccharides; Antioxidant activity; Free radical scavenging activity; LIPID-PEROXIDATION; MUSHROOMS; ANTITUMOR; EXTRACTS; DAMAGE;
D O I
10.1016/j.foodchem.2013.10.029
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The antioxidant activities of two homogeneous polysaccharides, water extraction of polysaccharide (W-PTR) and alkali extraction of polysaccharide (A-PTR) from Pleurotus tuber-regium (Fr.) Sing, were evaluated. Results showed that W-PTR was stronger than A-PTR in O-2(-center dot) scavenging activity, while A-PTR was stronger than W-PTR in the scavenging activities to (OH)-O-center dot, DPPH center dot, inhibition effects on liver lipid peroxidation, liver mitochondria swelling, and red blood cell (RBC) hemolysis. At concentration of 0.3 g/L, the O-2(-center dot) scavenging activity of W-PTR and A-PTR were 85.7% and 71.7%. At concentration of 0.25 g/L, the (OH)-O-center dot scavenging activity of W-PTR and A-PTR were 64.20% and 74.97%. At the concentration of 0.3 g/L, the lipid peroxidation inhibition effects of A-PTR were 79.37%. At concentration of 0.8 g/L, the hemolysis inhibition rate of A-PTR was 77.16%. The polysaccharides of P. tuber-regium had strong antioxidant potency and might be exploited as effective natural antioxidant to alleviate oxidative stress. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:351 / 356
页数:6
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