Pediatric otogenic cerebral venous sinus thrombosis: a case report and a literature review

被引:8
作者
Castellazzi, Massimo Luca [1 ]
di Pietro, Giada Maria [2 ]
Gaffuri, Michele [3 ,4 ]
Torretta, Sara [3 ,4 ]
Conte, Giorgio [5 ]
Folino, Francesco [2 ]
Aleo, Sebastiano [6 ]
Bosis, Samantha [6 ]
Marchisio, Paola [6 ,7 ]
机构
[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Paediat Emergency Dept, Milan, Italy
[2] Univ Milan, Milan, Italy
[3] Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policln, Dept Otolaryngol & Head & Neck Surg, Milan, Italy
[4] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy
[5] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Neuroradiol Unit, Milan, Italy
[6] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Paediat Highly Intens Care Unit, Milan, Italy
[7] Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy
关键词
Acute otitis media; Acute mastoiditis; Cerebral venous sinus thrombosis; Fusobacterium necrophorum; Children; MOLECULAR-WEIGHT HEPARIN; OTITIS-MEDIA; CHILDREN; MANAGEMENT; MASTOIDITIS; PREVENTION; THERAPY;
D O I
10.1186/s13052-020-00882-9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background Cerebral venous sinus thrombosis in children is a rare but potentially fatal complication of acute mastoiditis, one of the most common pediatric infectious diseases. Due to its subtle clinical presentation, suspicion is essential for a prompt diagnosis and appropriate management. Unfortunately, no standard treatment options are available. To discuss the possible clinical presentation, microbiology, and management, we here report the case of a child with otogenic cerebral venous sinus thrombosis and perform a literature review starting from 2011. Case presentation The child, a 10-months-old male, presented clinical signs of right acute otitis media and mastoiditis. Brain computed tomography scan detected right sigmoid and transverse sinus thrombosis, as well as a subperiosteal abscess.Fusobacterium necrophorumandHaemophilus Influentiaewere detected on cultural sampling. A multidisciplinary approach along with a combination of medical and surgical therapy allowed the patient's full recovery. Conclusion Cerebral venous sinus thrombosis is a rare but severe complication of acute otitis media and mastoiditis. The management of this pathological condition is always challenging and an interdisciplinary approach is frequently required. Current therapeutic options include a combination of medical and surgical therapy. A patient-centered approach should guide timing and treatment management.
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页数:11
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