Congenital syphilis: Subtle presentation of fulminant disease

被引:11
作者
Bennett, ML [1 ]
Lynn, AW [1 ]
Klein, LE [1 ]
Balkowiec, KS [1 ]
机构
[1] UNIV S CAROLINA,DEPT DERMATOL,COLUMBIA,SC 29203
关键词
D O I
10.1016/S0190-9622(97)80415-X
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The incidence of congenital syphilis has experienced a foul-fold to fivefold increase in 6 years. It is a completely preventable disease whose clinical spectrum ranges from asymptomatic infection, to fulminant sepsis, to death. Congenital syphilis was diagnosed in a 6-week-old infant whose mother was negative for the disease by prenatal screen. The otherwise well child presented with a generalized, papulosquamous eruption of 3 weeks' duration but within hours multisystem failure developed from overwhelming treponemal sepsis. Factors related to increased incidence, problems in serodiagnosis, manifestations of the early versus late forms of the disease, and recommendations for evaluation and treatment are illustrated by this patient and are discussed.
引用
收藏
页码:351 / 354
页数:4
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