Methamphetamine-Associated Cardiomyopathy

被引：105

作者：

Won, Sekon ^{[1
]}

Hong, Robert A. ^{[1
]}

Shohet, Ralph V. ^{[1
]}

Seto, Todd B. ^{[1
]}

Parikh, Nisha I. ^{[1
]}

机构：

[1] Univ Hawaii Manoa, John A Burns Sch Med, Honolulu, HI 96822 USA

来源：

CLINICAL CARDIOLOGY | 2013年 / 36卷 / 12期

关键词：

HEART-FAILURE; PHARMACOKINETICS; MANAGEMENT; SMOKING;

D O I：

10.1002/clc.22195

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Methamphetamine and related compounds are now the second most commonly used illicit substance worldwide, after cannabis. Reports of methamphetamine-associated cardiomyopathy (MAC) are increasing, but MAC has not been well reviewed. This analysis of MAC will provide an overview of the pharmacology of methamphetamine, historical perspective and epidemiology, a review of case and clinical studies, and a summary of the proposed mechanisms for MAC. Clinically, many questions remain, including the appropriate therapeutic interventions for MAC, the incidence and prevalence of cardiac pathology in methamphetamine users, risk factors for developing MAC, and prognosis of these patients. In conclusion, recognition of the significance of MAC among physicians and other medical caregivers is important given the growing use of methamphetamine and related stimulants worldwide.

引用

页码：737 / 742

页数：6

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