Autoimmune Manifestations in Large Granular Lymphocyte Leukemia

被引：48

作者：

Bockorny, Bruno ^{[1
]}

Dasanu, Constantin A. ^{[2
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Dept Med, Med Ctr, Farmington, CT 06030 USA

[2] St Francis Hosp & Med Ctr, Dept Hematol Oncol, Hartford, CT USA

来源：

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2012年 / 12卷 / 06期

关键词：

Autoimmune disorder; Felty's syndrome; Large granular lymphocyte; LGL leukemia; Rheumatoid arthritis; RED-CELL APLASIA; T-CELL; LYMPHOPROLIFERATIVE DISEASE; RHEUMATOID-ARTHRITIS; SJOGRENS-SYNDROME; LGL LEUKEMIA; CLINICAL-FEATURES; FELTYS-SYNDROME; CYCLOSPORINE-A; FAS LIGAND;

D O I：

10.1016/j.clml.2012.06.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Large granular lymphocyte (LGL) leukemia features a group of indolent lymphoproliferative diseases that display a strong association with various autoimmune conditions. Notwithstanding, these autoimmune conditions have not been comprehensively characterized or systematized to date. As a result, their clinical implications remain largely unknown. The authors offer a comprehensive review of the existing literature on various autoimmune conditions documented in the course of T-cell LGL (T-LGL) leukemia. Though some of them are thought be secondary to the LGL leukemia, others could be primary and might even play a role in its pathogenesis. A considerable clinico-laboratory overlap between T-LGL leukemia associated with rheumatoid arthritis and Felty's syndrome suggests that they are just different eponyms for the same clinical entity. Clinical Lymphoma, Myeloma & Leukemia, Vol. 12, No. 6, 400-5 Published by Elsevier Inc.

引用

页码：400 / 405

页数：6

共 85 条

[1] Aggressive T-cell large granular lymphocyte leukemia: A case report and review of the literature [J].

Alekshun, Todd J. ;

Tao, Jianguo ;

Sokol, Lubomir .

AMERICAN JOURNAL OF HEMATOLOGY, 2007, 82 (06) :481-485

[2]

[Anonymous], EXPERT REV HEMATOL

[3]

[Anonymous], BLOOD

[4]

[Anonymous], HEMATOL J S

[5] T-cell large granular lymphocytic (T-LGL) leukemia: Experience in a single institution over 8 years [J].

Aribi, Ahmed ;

Huh, Yang ;

Keating, Michael ;

O'Brien, Susan ;

Ferrajoli, Alessandra ;

Faderl, Stefan ;

Wierda, William ;

Kantarjian, Hagop ;

Ravandi, Farhad .

LEUKEMIA RESEARCH, 2007, 31 (07) :939-945

[6] Alemtuzumab induced complete remission of therapy-resistant pure red cell aplasia [J].

Au, WY ;

Lam, CCK ;

Chim, CS ;

Pang, AWK ;

Kwong, YL .

LEUKEMIA RESEARCH, 2005, 29 (10) :1213-1215

[7] Felty's syndrome [J].

Balint, GR ;

Balint, PV .

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2004, 18 (05) :631-645

[8] Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases [J].

Bareau, Benoit ;

Rey, Jerome ;

Hamidou, Mohamed ;

Donadieu, Jean ;

Morcet, Jeff ;

Reman, Oumedaly ;

Schleinitz, Nicolas ;

Tournilhac, Olivier ;

Roussel, Mikael ;

Fest, Thierry ;

Lamy, Thierry .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (09) :1534-1541

[9] HLA-DR4 predicts haematological response to cyclosporine in T-large granular lymphocyte lymphoproliferative disorders [J].

Battiwalla, M ;

Melenhorst, J ;

Saunthararajah, Y ;

Nakamura, R ;

Molldrem, J ;

Young, NS ;

Barrett, AJ .

BRITISH JOURNAL OF HAEMATOLOGY, 2003, 123 (03) :449-453

[10] Clinical spectrum of γδ+ T cell LGL leukemia:: Analysis of 20 cases [J].

Bourgault-Rouxel, A. S. ;

Loughran, T. P., Jr. ;

Zambello, R. ;

Epling-Burnette, P. K. ;

Semenzato, G. ;

Donadieu, J. ;

Amiot, L. ;

Fest, T. ;

Lamy, T. .

LEUKEMIA RESEARCH, 2008, 32 (01) :45-48

← 1 2 3 4 5 6 7 8 9 →