Should modern imaging be part of remission criteria in rheumatoid arthritis?

被引:46
作者
Haavardsholm, Espen A. [1 ]
Lie, Elisabeth [1 ]
Lillegraven, Siri [1 ]
机构
[1] Diakonhjemmet Hosp, Dept Rheumatol, N-0319 Oslo, Norway
来源
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2012年 / 26卷 / 06期
关键词
Rheumatoid arthritis; Remission; Magnetic resonance imaging; Ultrasonography; MODIFYING ANTIRHEUMATIC DRUGS; BONE-MARROW EDEMA; PREDICTS EROSIVE PROGRESSION; SMALL JOINT INVOLVEMENT; LOW DISEASE-ACTIVITY; 1-YEAR FOLLOW-UP; AMERICAN-COLLEGE; CLINICAL REMISSION; RHEUMATOLOGY/EUROPEAN LEAGUE; RADIOGRAPHIC PROGRESSION;
D O I
10.1016/j.berh.2012.10.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
With recent improvements in the treatment of rheumatoid arthritis (RA), remission has become an achievable goal for a large proportion of RA patients, and remission is now a defined target in current RA guidelines. However, studies have shown that progression of radiographic joint damage may occur in clinical remission, regardless of the choice of remission definition. Subclinical inflammation detected by modern imaging techniques such as ultrasonography and magnetic resonance imaging is present in the majority of patients in clinical remission, and is associated with progressive joint damage and disease activity flare in these patients. This chapter aims to assess the importance of imaging findings in RA patients in clinical remission and to discuss the possible role of modern imaging in future remission criteria. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:767 / 785
页数:19
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