Levamisole-Adulterated Cocaine: A Case Series

被引：12

作者：

Morris, Gerald W., Jr.

Mason, Bryan C.

Sprunger, Rachael Harris ^{[3
]}

Harris, Holly Hake ^{[4
,5
]}

White, Luke A. ^{[2
]}

Patterson, Dale A. ^{[1
]}

机构：

[1] Mem Hosp, Family Med Residency Program, South Bend, IN 46601 USA

[2] Mem Hosp, Dept Internal Med, South Bend, IN 46601 USA

[3] Midwestern Univ, Chicago, IL USA

[4] S Bend Clin, South Bend, IN USA

[5] Indiana Univ Sch Med, South Bend, IN USA

来源：

JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE | 2012年 / 25卷 / 04期

关键词：

Case Reports; Cocaine; Levamisole; Leukopenia; Purpura; Vasculitis; VASCULITIS; PURPURA; VASCULOPATHY; NEUTROPENIA; USERS; EARS;

D O I：

10.3122/jabfm.2012.04.110287

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The percentage of cocaine adulterated with levamisole is steadily increasing in the United States. In susceptible persons, this combination of drugs leads to a clinical syndrome that can include leukopenia and cutaneous manifestations. Many patients also demonstrate positive autoimmune markers. Biopsies of skin lesions often reveal a thrombotic pattern, leukocytoclastic vasculitis, or both. We report 2 cases of this clinical phenomenon, one of which was severe enough to require skin grafting. It is important for clinicians be aware of this emerging public health threat. (J Am Board Fam Med 2012;25:531-535.)

引用

页码：531 / 535

页数：5

共 16 条

[1]

Ann Marie M., 2005, MICROGRAM J, V3, P134

[2]

[Anonymous], STRANGER 0817

[3]

Brackney M., 2009, Morbidity and Mortality Weekly Report, V58, P1381

[4] Prevalence of Levamisole in Urine Toxicology Screens Positive for Cocaine in an Inner-City Hospital [J].